OBJECT: To quantitatively compare different microsurgical and endoscopic approaches to the middle cranial fossa in a preclinical setting with a novel, computer-based research method. METHODS: Different approaches were performed bilaterally in 5 head and neck specimens that underwent high-resolution computed tomography scans: five transcranial anterolateral (supraorbital, mini-pterional, pterional, pterional-transzygomatic, fronto-temporal-orbito-zygomatic) without and with anterior clinoidectomy; two transcranial lateral (subtemporal and subtemporal-transzygomatic); two endoscopic transnasal (transpterygoid, transpterygoid to infratemporal fossa); two endoscopic transorbital (superior eyelid and inferolateral) and endoscopic transmaxillary. A dedicated navigation system was used to quantify surgical working volumes and exposure of different areas of the middle cranial fossa (ApproachViewer, part of GTx-Eyes II, University Health Network, Toronto, Canada). Statistical analysis was performed using a mixed linear model with bootstrap re-sampling. RESULTS: Endoscopic transnasal and fronto-temporal-orbito-zygomatic approaches with anterior clinoidectomy showed the largest surgical volumes. Endoscopic approaches allowed a wider exposure of medial anatomical surfaces (e.g. the petrous apex) compared to transcranial ones. Transcranial approaches with larger craniotomies allowed the widest exposure of supero-medial anatomical structures (e.g. roof of cavernous sinus). The resection of the zygomatic arch allowed exposure of more medial surfaces with an inferior to superior trajectory. CONCLUSIONS: This study implemented a novel neuronavigation-based research method to quantitatively compare different approaches to the middle cranial fossa; its results might guide, after consideration of clinical implications, the choice of the neurosurgical approach to different areas of this complex skull base region.
Quantitative Anatomical Comparison of Anterior, Antero-Lateral and Lateral, Microsurgical and Endoscopic Approaches to the Middle Cranial Fossa
Saraceno, Giorgio;Agosti, Edoardo;Buffoli, Barbara;Ferrari, Marco;Raffetti, Elena;Belotti, Francesco;Ravanelli, Marco;Mattavelli, Davide;Schreiber, Alberto;Hirtler, Lena;Rodella, Luigi F;Maroldi, Roberto;Nicolai, Piero;Kucharczyk, Walter;Fontanella, Marco M;Doglietto, Francesco
2020-01-01
Abstract
OBJECT: To quantitatively compare different microsurgical and endoscopic approaches to the middle cranial fossa in a preclinical setting with a novel, computer-based research method. METHODS: Different approaches were performed bilaterally in 5 head and neck specimens that underwent high-resolution computed tomography scans: five transcranial anterolateral (supraorbital, mini-pterional, pterional, pterional-transzygomatic, fronto-temporal-orbito-zygomatic) without and with anterior clinoidectomy; two transcranial lateral (subtemporal and subtemporal-transzygomatic); two endoscopic transnasal (transpterygoid, transpterygoid to infratemporal fossa); two endoscopic transorbital (superior eyelid and inferolateral) and endoscopic transmaxillary. A dedicated navigation system was used to quantify surgical working volumes and exposure of different areas of the middle cranial fossa (ApproachViewer, part of GTx-Eyes II, University Health Network, Toronto, Canada). Statistical analysis was performed using a mixed linear model with bootstrap re-sampling. RESULTS: Endoscopic transnasal and fronto-temporal-orbito-zygomatic approaches with anterior clinoidectomy showed the largest surgical volumes. Endoscopic approaches allowed a wider exposure of medial anatomical surfaces (e.g. the petrous apex) compared to transcranial ones. Transcranial approaches with larger craniotomies allowed the widest exposure of supero-medial anatomical structures (e.g. roof of cavernous sinus). The resection of the zygomatic arch allowed exposure of more medial surfaces with an inferior to superior trajectory. CONCLUSIONS: This study implemented a novel neuronavigation-based research method to quantitatively compare different approaches to the middle cranial fossa; its results might guide, after consideration of clinical implications, the choice of the neurosurgical approach to different areas of this complex skull base region.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
