A miR-137–Related Biological Pathway of Risk for Schizophrenia Is Associated With Human Brain Emotion Processing

Background: miR-137 is a microRNA involved in brain development, regulating neurogenesis and neuronal maturation. Genome-wide association studies have implicated miR-137 in schizophrenia risk but do not explain its involvement in brain function and underlying biology. Polygenic risk for schizophrenia mediated by miR-137 targets is associated with working memory, although other evidence points to emotion processing. We characterized the functional brain correlates of miR-137 target genes assoc...

Naringerin as candidate drug against SARS-CoV-2: The role for TPC2 genomic variants in COVID-19

A systematic approach to develop safety-related undesired event databases for Machine Learning analyses: Application to confined space incidents

In Occupational Safety and Health (OSH) and operational safety, confined spaces are high-risk working areas, where frequent serious and fatal incidents occur. However, there is a limited use of data-driven approaches based on Machine Learning (ML) techniques for learning from such incidents. In this context, our study proposes a systematic approach to develop a structured database suitable for ML-based analyses, considering various data sources with unstructured or semi-structured data. The a...

Safety Role and Contribution to Industrial Sustainability

This Special Issue “Safety Role and Contribution to Industrial Sustainability” aims to stress the relevance of sustainable development by promoting research on the role of Occupational Safety and Health (OSH) in enhancing industrial sustainability, with respect to three integrated dimensions (i.e., economic, environmental, and social). Although many leading companies have started considering sustainability as a key part of their business strategy, the social dimension of sustainability, and p...