Excerpt: Adrenocortical carcinoma (ACC) is a rare endocrine neoplasia, characterized by an overall dismal prognosis and its clinical manifestations are the consequence of either steroid excess or tumor mass progression. Surgery is the mainstay of therapy. For patients with locally advanced or metastatic ACC, not amenable to surgery, Mitotane and cytotoxic chemotherapy (with etoposide, doxorubicin and cisplatin - EDP scheme) are the systemic treatments currently in use.

Immunotherapy failure in adrenocortical cancer: where next?

Cosentini, Deborah;Grisanti, Salvatore;LAGANA', MARTA;Fiorentini, Chiara;Sigala, Sandra;Berruti, Alfredo
2018-01-01

Abstract

Excerpt: Adrenocortical carcinoma (ACC) is a rare endocrine neoplasia, characterized by an overall dismal prognosis and its clinical manifestations are the consequence of either steroid excess or tumor mass progression. Surgery is the mainstay of therapy. For patients with locally advanced or metastatic ACC, not amenable to surgery, Mitotane and cytotoxic chemotherapy (with etoposide, doxorubicin and cisplatin - EDP scheme) are the systemic treatments currently in use.
File in questo prodotto:
File Dimensione Formato  
Endocrine Connections] Immunotherapy failure in adrenocortical cancer_ where next_.pdf

accesso aperto

Descrizione: published paper
Tipologia: Documento in Post-print
Licenza: Dominio pubblico
Dimensione 508.58 kB
Formato Adobe PDF
508.58 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11379/515606
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 17
  • Scopus 36
  • ???jsp.display-item.citation.isi??? 35
social impact