Metformin treatment may induce a decrease/suppression in serum TSH levels, mimicking sub-clinical hyperthyroidism (SHT). The aim of the present study was to retrospectively evaluate changes in several electrocardiographic indices in euthyroid subjects with diabetes who, after starting metformin treatment, developed a low serum TSH as compared to patients with SHT resulting from an underlying thyroid disease or TSH suppressive treatment with L-thyroxine.

Metformin-induced thyrotropin suppression is not associated with cardiac effects

CAPPELLI, Carlo;PIROLA, Ilenia;AGOSTI, BARBARA;SALVETTI, Massimo;CASTELLANO, Maurizio
2014-01-01

Abstract

Metformin treatment may induce a decrease/suppression in serum TSH levels, mimicking sub-clinical hyperthyroidism (SHT). The aim of the present study was to retrospectively evaluate changes in several electrocardiographic indices in euthyroid subjects with diabetes who, after starting metformin treatment, developed a low serum TSH as compared to patients with SHT resulting from an underlying thyroid disease or TSH suppressive treatment with L-thyroxine.
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Licenza: PUBBLICO - Pubblico senza Copyright
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11379/484047
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