In this paper we propose an inversion-based methodology for the computation of a feedforward action for the propofol intravenous administration during the induction of hypnosis in general anesthesia. In particular, the typical initial bolus is substituted with a command signal that is obtained by predefining a desired output and by applying an input-output inversion procedure. The robustness of the method has been tested by considering a set of patients with different model parameters, which is representative of a large population.
Inversion-based propofol dosing for intravenous induction of hypnosis
PADULA, Fabrizio;LATRONICO, Nicola;VISIOLI, Antonio;
2016-01-01
Abstract
In this paper we propose an inversion-based methodology for the computation of a feedforward action for the propofol intravenous administration during the induction of hypnosis in general anesthesia. In particular, the typical initial bolus is substituted with a command signal that is obtained by predefining a desired output and by applying an input-output inversion procedure. The robustness of the method has been tested by considering a set of patients with different model parameters, which is representative of a large population.File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
Padula_et_al.pdf
solo utenti autorizzati
Tipologia:
Documento in Post-print
Licenza:
DRM non definito
Dimensione
4.34 MB
Formato
Adobe PDF
|
4.34 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
