FRA, ANNAMARIA
 Distribuzione geografica
Continente #
NA - Nord America 4.060
EU - Europa 2.205
AS - Asia 1.779
SA - Sud America 332
AF - Africa 32
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 6
Totale 8.423
Nazione #
US - Stati Uniti d'America 3.995
CN - Cina 652
PL - Polonia 630
SG - Singapore 563
IT - Italia 343
UA - Ucraina 321
BR - Brasile 282
DE - Germania 247
GB - Regno Unito 234
HK - Hong Kong 205
FI - Finlandia 131
VN - Vietnam 120
TR - Turchia 86
RU - Federazione Russa 77
IE - Irlanda 67
IN - India 55
FR - Francia 35
CA - Canada 31
MX - Messico 25
BD - Bangladesh 24
BE - Belgio 23
SE - Svezia 23
AR - Argentina 17
CH - Svizzera 14
ES - Italia 13
ZA - Sudafrica 13
JP - Giappone 12
ID - Indonesia 11
AU - Australia 9
IQ - Iraq 9
NL - Olanda 9
VE - Venezuela 9
LT - Lituania 8
AT - Austria 7
PK - Pakistan 7
AE - Emirati Arabi Uniti 6
CO - Colombia 6
IL - Israele 6
PY - Paraguay 6
EC - Ecuador 5
EU - Europa 5
JM - Giamaica 5
AZ - Azerbaigian 4
CZ - Repubblica Ceca 4
EG - Egitto 4
DK - Danimarca 3
DZ - Algeria 3
JO - Giordania 3
KE - Kenya 3
MU - Mauritius 3
PE - Perù 3
PH - Filippine 3
PT - Portogallo 3
RO - Romania 3
SA - Arabia Saudita 3
BG - Bulgaria 2
BY - Bielorussia 2
CL - Cile 2
CR - Costa Rica 2
GR - Grecia 2
HR - Croazia 2
MA - Marocco 2
QA - Qatar 2
UZ - Uzbekistan 2
AL - Albania 1
BO - Bolivia 1
BW - Botswana 1
ET - Etiopia 1
GE - Georgia 1
GY - Guiana 1
HU - Ungheria 1
KG - Kirghizistan 1
KR - Corea 1
LB - Libano 1
LK - Sri Lanka 1
LY - Libia 1
MY - Malesia 1
SV - El Salvador 1
TN - Tunisia 1
TT - Trinidad e Tobago 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 8.423
Città #
Warsaw 629
Fairfield 452
Ashburn 345
Singapore 290
Woodbridge 289
Jacksonville 235
Chandler 217
Hong Kong 201
Wilmington 197
Houston 194
Ann Arbor 192
Cambridge 192
Seattle 189
Beijing 182
Princeton 112
Brescia 110
Lancaster 102
New York 95
Los Angeles 79
Nanjing 74
Chicago 70
Dearborn 67
Dublin 66
Helsinki 63
Munich 61
Istanbul 59
The Dalles 50
Des Moines 44
Buffalo 43
Ho Chi Minh City 40
San Diego 33
San Francisco 31
Nanchang 29
Rome 29
Shanghai 29
Dong Ket 28
São Paulo 27
Changsha 25
London 25
Milan 25
Moscow 25
Tianjin 24
Turku 24
Dallas 23
Jiaxing 23
Redondo Beach 23
Brussels 22
Shenyang 21
Salt Lake City 20
Hanoi 18
Hebei 18
Jinan 18
Tampa 16
Brooklyn 15
Elk Grove Village 15
Indianapolis 14
Kocaeli 14
Phoenix 14
Boston 13
Guangzhou 13
Denver 11
Hangzhou 11
Jakarta 11
Rio de Janeiro 11
Kunming 10
Lugano 10
Montreal 10
Santa Clara 10
Zhengzhou 10
Frankfurt am Main 9
Lappeenranta 9
Miami 9
Pune 9
Saratoga Springs 9
St Louis 9
Tokyo 9
Toronto 9
Belo Horizonte 8
Chennai 8
Council Bluffs 8
Johannesburg 8
Lanzhou 8
Manchester 8
Verona 8
Mexico City 7
Nuremberg 7
Orange 7
Orem 7
Taizhou 7
Boardman 6
Charlotte 6
Kansas City 6
Las Vegas 6
Ningbo 6
Salvador 6
Trieste 6
Villongo 6
Ankara 5
Atlanta 5
Brasília 5
Totale 5.913
Nome #
The pathological Trento variant of alpha-1-antitrypsin (E75V) shows non-classical behaviour during polymerization 295
Cysteines as Redox Molecular Switches and Targets of Disease 256
Intermittent C1-Inhibitor Deficiency Associated with Recessive Inheritance: Functional and Structural Insight 252
Human iPSC-Derived 3D Hepatic Organoids in a Miniaturized Dynamic Culture System 243
Characterisation of a type II functionally-deficient variant of alpha-1-antitrypsin discovered in the general population 227
Stability and structural change in the pathological polymerisation of alpha 1-antitrypsin 192
Different molecular behavior of CD40 mutants causing hyper-IgM syndrome. 189
Quality control of ER synthesized proteins: an exposed thiol group as a three-way switch mediating assembly, retention and degradation 188
Developmental regulation of IgM secretion: the role of the carboxy-terminal cysteine 185
Real-world clinical applicability of pathogenicity predictors assessed on SERPINA1 mutations in alpha-1-antitrypsin deficiency 173
Identification and characterisation of eight novel SERPINA1 null mutations. 171
A photo-reactive derivative of ganglioside GM1 specifically cross-links VIP21-caveolin on the cell surface 160
Caveolin-1 and -2 in the exocytic pathway of MDCK cells 159
Cutting edge: scavenging of inflammatory CC chemokines by the promiscuous putatively silent chemokine receptor D6 156
Characterization of a mouse endothelium lymphatic cell line. 156
The Decrease of Mineralcorticoid Receptor Drives Angiogenic Pathways in Colorectal Cancer 155
Aberrant disulphide bonding contributes to the ER retention of alpha1-antitrypsin deficiency variants 154
Cellular models for the serpinopathies 154
De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin 149
Alpha1-antitrypsin deficiency: a twenty-five years' experience. 146
Degradation of unassembled soluble Ig subunits by cytosolic proteasomes: evidence that retrotranslocation and degradation are coupled events 145
Functional characterization of amino acid variants of the reactive-center-loop of alpha-1-antitrypsin 145
Exposed thiols confer localization in the endoplasmic reticulum by retention rather than retrieval 142
Phenotypic behavior of C2C12 myoblasts upon expression of the dystrophy-related caveolin-3 P104L and TFT mutants 139
Molecular characterization of the new defective P(brescia) alpha1-antitrypsin allele. 139
Development of a novel assay to measure alpha-1-antitrypsin inhibitory activity toward neutrophil elastase 136
Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin 136
CHOP-independent apoptosis and pathway-selective induction of the UPR in developing plasma cells 134
Progressively impaired proteasomal capacity during terminal plasma cell differentiation 131
Three new alpha1-antitrypsin deficiency variants help to define a C-terminal region regulating conformational change and polymerization. 130
Differential recognition and scavenging of native and truncated macrophage-derived chemokine (macrophage-derived chemokine/CC chemokine ligand 22) by the D6 decoy receptor 129
Generation and characterization of a mouse lymphatic endothelial cell line 126
The efficiency of cysteine-mediated intracellular retention determines the differential fate of secretory IgA and IgM in B and plasma cells 124
A case of remittent C1-inhibitor deficiency 124
Fab fragment of an antibody selective for wild-type alpha-1-antitrypsin in complex with its antigen 124
The endoplasmic reticulum as a site of protein degradation 122
Fab fragment of an antibody selective for wild-type alpha-1-antitrypsin 121
Aberrant disulphide interactions contribute to the secretory deficiency of Alpha 1-Antitrypsin mutants 118
Mechanisms of interleukin-6 protection against ischemia-reperfusion injury in rat liver 118
Genomic organization and transcriptional analysis of the human genes coding for caveolin-1 and caveolin-2 116
Human caveolin-1 and caveolin-2 are closely linked genes colocalized with WI-5336 in a region of 7q31 frequently deleted in tumors 115
Molecular characterization of new variants associated with alpha-1-antitrypsin deficiency (AATD) 114
Patogenesi delle malattie da alterato trasporto e accumulo proteico nella via secretoria 112
Different mechanisms cause ER retention of rare alpha1-antitrypsin deficiency variants 111
Assembly and secretion of antibodies during B cell development 105
Detergent-insoluble glycolipid microdomains in lymphocytes in the absence of caveolae 105
Heteropolymerization of α-1-antitrypsin mutants in cell models mimicking heterozygosity 101
Characterization of alpha-1 antitrypsin mutants with an alternative polymerisation mechanism 99
Modulating secretion of antibodies 99
HIGM3 patients: understanding the mutation effect to develop a therapeutic approach 98
Polymers of Z α1-antitrypsin are secreted in cell models of disease 95
Structural characterisation of tissue-derived, disease-associated polymers of alpha-1-antitrypsin using conformation-selective antibodies and single-particle reconstructions from electron microscopy images 93
Regolazione dei geni coinvolti nella patogenesi dell'angioedema ereditario da carenza di C1 inibitore 86
Comprehensive Clinical Diagnostic Pipelines Reveal New Variants in Alpha-1 Antitrypsin Deficiency 83
Identification and characterisation of seven novel SERPINA1 null mutations 83
Quantification of circulating alpha-1-antitrypsin polymers in dried blood spots 83
Characterization of Novel Alpha-1-Antitrypsin Coding Variants in a Mammalian Cellular Model 81
The molecular species responsible for α1 -antitrypsin deficiency are suppressed by a small molecule chaperone 81
Computational prediction of (alpha-1antitrypsin)-elastase Michaelis complex reveals an exosite contributing to high-affinity interaction 76
Probing of the reactive center loop region of alpha-1-antitrypsin by mutagenesis predicts new type-2 dysfunctional variants 70
The importance of N186 in the alpha-1-antitrypsin shutter region is revealed by the novel bologna deficiency variant 67
Quantification of circulating alpha-1-antitrypsin polymers associated with different SERPINA1 genotypes 66
Neuroserpin: structure, function, physiology and pathology 61
Identification and characterisation of twenty-two novel SERPINA1 pathological mutations 60
High-resolution characterization of ex vivo AAT polymers by solution-state NMR spectroscopy 56
Clinical and molecular characterisation of new variants associated to alpha-1-antitrypsin deficiency 51
Identification of an exosite at the neutrophil elastase/alpha‐1‐antitrypsin interface 37
Susceptibility of alpha-1 antitrypsin deficiency variants to polymer-blocking therapy 19
Totale 8.666
Categoria #
all - tutte 37.841
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.841


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021721 0 0 0 0 0 123 74 113 126 131 83 71
2021/2022530 38 94 14 16 6 28 43 37 21 98 35 100
2022/2023561 73 21 26 43 50 125 2 63 85 12 21 40
2023/2024521 39 14 41 43 26 102 20 27 114 15 11 69
2024/20251.603 18 13 14 151 175 124 145 45 139 91 455 233
2025/20261.449 288 276 165 359 308 53 0 0 0 0 0 0
Totale 8.666