FRA, ANNAMARIA
 Distribuzione geografica
Continente #
NA - Nord America 3.104
EU - Europa 1.763
AS - Asia 848
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 5
SA - Sud America 5
AF - Africa 4
Totale 5.734
Nazione #
US - Stati Uniti d'America 3.093
PL - Polonia 612
CN - Cina 427
UA - Ucraina 309
IT - Italia 256
GB - Regno Unito 185
SG - Singapore 163
DE - Germania 162
HK - Hong Kong 101
FI - Finlandia 91
TR - Turchia 73
IE - Irlanda 58
VN - Vietnam 35
IN - India 33
BE - Belgio 20
FR - Francia 19
SE - Svezia 17
RU - Federazione Russa 14
CA - Canada 9
ID - Indonesia 9
AU - Australia 5
EU - Europa 5
AR - Argentina 4
CZ - Repubblica Ceca 4
ES - Italia 4
CH - Svizzera 3
JP - Giappone 3
MU - Mauritius 3
RO - Romania 3
MX - Messico 2
NL - Olanda 2
PT - Portogallo 2
AZ - Azerbaigian 1
CL - Cile 1
DK - Danimarca 1
JO - Giordania 1
KG - Kirghizistan 1
KR - Corea 1
LT - Lituania 1
ZA - Sudafrica 1
Totale 5.734
Città #
Warsaw 612
Fairfield 452
Woodbridge 289
Ashburn 246
Jacksonville 235
Chandler 217
Wilmington 193
Ann Arbor 192
Cambridge 190
Houston 189
Seattle 184
Singapore 135
Princeton 112
Lancaster 100
Hong Kong 98
Beijing 90
Brescia 88
Nanjing 74
Dearborn 67
Dublin 58
Istanbul 57
New York 53
Helsinki 49
San Diego 33
Nanchang 29
Dong Ket 28
Shanghai 28
Jiaxing 23
Milan 22
Shenyang 21
Tianjin 21
Changsha 20
Brussels 19
Des Moines 18
Hebei 18
London 16
Jinan 15
Kocaeli 14
Rome 12
Hangzhou 11
Kunming 10
Phoenix 10
Zhengzhou 10
Jakarta 9
Pune 9
Saratoga Springs 9
Verona 8
Guangzhou 7
Lanzhou 7
Lappeenranta 7
Los Angeles 7
Orange 7
Taizhou 7
Boardman 6
Ho Chi Minh City 6
Ningbo 6
San Francisco 6
Villongo 6
Frankfurt am Main 5
Monza 5
Brno 4
Buenos Aires 4
Changchun 4
Hefei 4
Indiana 4
Kilburn 4
Rhinelander 4
Toronto 4
Borgosatollo 3
Falkenstein 3
Haikou 3
Miami 3
Norwalk 3
Oxford 3
Barcelona 2
Bergamo 2
Brooklyn 2
Castiglione Chiavarese 2
Chicago 2
Cremona 2
East Brunswick 2
Ferrara 2
Guidonia 2
Hounslow 2
Leicester 2
Lonato 2
Lucca 2
Madrid 2
Melbourne 2
Melegnano 2
Mumbai 2
Naples 2
New Bedfont 2
Newham 2
Nürnberg 2
Porto 2
Querétaro City 2
Romola 2
San Mateo 2
Sheffield 2
Totale 4.577
Nome #
The pathological Trento variant of alpha-1-antitrypsin (E75V) shows non-classical behaviour during polymerization 247
Cysteines as Redox Molecular Switches and Targets of Disease 226
Intermittent C1-Inhibitor Deficiency Associated with Recessive Inheritance: Functional and Structural Insight 216
Characterisation of a type II functionally-deficient variant of alpha-1-antitrypsin discovered in the general population 186
Stability and structural change in the pathological polymerisation of alpha 1-antitrypsin 171
Quality control of ER synthesized proteins: an exposed thiol group as a three-way switch mediating assembly, retention and degradation 164
Developmental regulation of IgM secretion: the role of the carboxy-terminal cysteine 161
Identification and characterisation of eight novel SERPINA1 null mutations. 157
Different molecular behavior of CD40 mutants causing hyper-IgM syndrome. 156
Caveolin-1 and -2 in the exocytic pathway of MDCK cells 133
Real-world clinical applicability of pathogenicity predictors assessed on SERPINA1 mutations in alpha-1-antitrypsin deficiency 127
A photo-reactive derivative of ganglioside GM1 specifically cross-links VIP21-caveolin on the cell surface 125
Exposed thiols confer localization in the endoplasmic reticulum by retention rather than retrieval 123
The Decrease of Mineralcorticoid Receptor Drives Angiogenic Pathways in Colorectal Cancer 121
De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin 116
Cutting edge: scavenging of inflammatory CC chemokines by the promiscuous putatively silent chemokine receptor D6 116
Cellular models for the serpinopathies 115
Aberrant disulphide bonding contributes to the ER retention of alpha1-antitrypsin deficiency variants 114
Degradation of unassembled soluble Ig subunits by cytosolic proteasomes: evidence that retrotranslocation and degradation are coupled events 113
Differential recognition and scavenging of native and truncated macrophage-derived chemokine (macrophage-derived chemokine/CC chemokine ligand 22) by the D6 decoy receptor 111
The efficiency of cysteine-mediated intracellular retention determines the differential fate of secretory IgA and IgM in B and plasma cells 109
Three new alpha1-antitrypsin deficiency variants help to define a C-terminal region regulating conformational change and polymerization. 107
Phenotypic behavior of C2C12 myoblasts upon expression of the dystrophy-related caveolin-3 P104L and TFT mutants 105
CHOP-independent apoptosis and pathway-selective induction of the UPR in developing plasma cells 105
Generation and characterization of a mouse lymphatic endothelial cell line 103
Characterization of a mouse endothelium lymphatic cell line. 103
Molecular characterization of the new defective P(brescia) alpha1-antitrypsin allele. 102
Genomic organization and transcriptional analysis of the human genes coding for caveolin-1 and caveolin-2 98
The endoplasmic reticulum as a site of protein degradation 98
Mechanisms of interleukin-6 protection against ischemia-reperfusion injury in rat liver 98
Alpha1-antitrypsin deficiency: a twenty-five years' experience. 97
Progressively impaired proteasomal capacity during terminal plasma cell differentiation 95
Human caveolin-1 and caveolin-2 are closely linked genes colocalized with WI-5336 in a region of 7q31 frequently deleted in tumors 90
Patogenesi delle malattie da alterato trasporto e accumulo proteico nella via secretoria 87
Detergent-insoluble glycolipid microdomains in lymphocytes in the absence of caveolae 85
A case of remittent C1-inhibitor deficiency 85
Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin 85
Fab fragment of an antibody selective for wild-type alpha-1-antitrypsin in complex with its antigen 82
Different mechanisms cause ER retention of rare alpha1-antitrypsin deficiency variants 80
Aberrant disulphide interactions contribute to the secretory deficiency of Alpha 1-Antitrypsin mutants 76
Assembly and secretion of antibodies during B cell development 75
Modulating secretion of antibodies 75
Polymers of Z α1-antitrypsin are secreted in cell models of disease 72
Functional characterization of amino acid variants of the reactive-center-loop of alpha-1-antitrypsin 72
Molecular characterization of new variants associated with alpha-1-antitrypsin deficiency (AATD) 71
Heteropolymerization of α-1-antitrypsin mutants in cell models mimicking heterozygosity 69
HIGM3 patients: understanding the mutation effect to develop a therapeutic approach 66
Fab fragment of an antibody selective for wild-type alpha-1-antitrypsin 66
Regolazione dei geni coinvolti nella patogenesi dell'angioedema ereditario da carenza di C1 inibitore 63
Identification and characterisation of seven novel SERPINA1 null mutations 57
The molecular species responsible for α1 -antitrypsin deficiency are suppressed by a small molecule chaperone 57
Structural characterisation of tissue-derived, disease-associated polymers of alpha-1-antitrypsin using conformation-selective antibodies and single-particle reconstructions from electron microscopy images 45
Quantification of circulating alpha-1-antitrypsin polymers in dried blood spots 42
Identification and characterisation of twenty-two novel SERPINA1 pathological mutations 31
The importance of N186 in the alpha-1-antitrypsin shutter region is revealed by the novel bologna deficiency variant 27
Comprehensive Clinical Diagnostic Pipelines Reveal New Variants in Alpha-1 Antitrypsin Deficiency 24
Human iPSC-Derived 3D Hepatic Organoids in a Miniaturized Dynamic Culture System 23
Clinical and molecular characterisation of new variants associated to alpha-1-antitrypsin deficiency 23
Development of a novel assay to measure alpha-1-antitrypsin inhibitory activity toward neutrophil elastase 23
Probing of the reactive center loop region of alpha-1-antitrypsin by mutagenesis predicts new type-2 dysfunctional variants 19
Characterization of Novel Alpha-1-Antitrypsin Coding Variants in a Mammalian Cellular Model 18
Neuroserpin: structure, function, physiology and pathology 18
Characterization of alpha-1 antitrypsin mutants with an alternative polymerisation mechanism 16
Computational prediction of (alpha-1antitrypsin)-elastase Michaelis complex reveals an exosite contributing to high-affinity interaction 13
Quantification of circulating alpha-1-antitrypsin polymers associated with different SERPINA1 genotypes 12
Totale 5.965
Categoria #
all - tutte 27.125
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 27.125


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.051 0 0 0 0 92 187 196 150 107 179 63 77
2020/20211.070 37 95 32 129 56 123 74 113 126 131 83 71
2021/2022530 38 94 14 16 6 28 43 37 21 98 35 100
2022/2023561 73 21 26 43 50 125 2 63 85 12 21 40
2023/2024521 39 14 41 43 26 102 20 27 114 15 11 69
2024/2025351 18 13 14 151 155 0 0 0 0 0 0 0
Totale 5.965