(Figure Presented) Nucleic acid-functionalized polyacrylamide chains that are cooperatively cross-linked by i-motif and nucleic acid duplex units yield, at pH 5.0, DNA hydrogels exhibiting shape-memory properties. Separation of the i-motif units at pH 8.0 dissolves the hydrogel into a quasi-liquid phase. The residual duplex units provide, however, a memory code in the quasi-liquid allowing the regeneration of the hydrogel shape at pH 5.0.

pH-stimulated DNA hydrogels exhibiting shape-memory properties

Cecconello A.;
2014-01-01

Abstract

(Figure Presented) Nucleic acid-functionalized polyacrylamide chains that are cooperatively cross-linked by i-motif and nucleic acid duplex units yield, at pH 5.0, DNA hydrogels exhibiting shape-memory properties. Separation of the i-motif units at pH 8.0 dissolves the hydrogel into a quasi-liquid phase. The residual duplex units provide, however, a memory code in the quasi-liquid allowing the regeneration of the hydrogel shape at pH 5.0.
2014
Inglese
27
1
73
78
6
Acrylamide; Gel; I-motif; Nucleic acid; Switch
8
info:eu-repo/semantics/article
262
Guo, W.; Lu, C. -H.; Orbach, R.; Wang, F.; Qi, X. -J.; Cecconello, A.; Seliktar, D.; Willner, I.
1 Contributo su Rivista::1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11379/623922
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