Accurate sensing of ion concentrations in body fluids is of importance to monitor cell functions, and any deviation of the concentration serves as a warning sign of pathophysiological conditions. Here, a fabrication approach for an integrated device consisting of two electrochemical transistors, capable of selective simultaneous detection between potassium and sodium ions in an analyte is demonstrated. A common in-plane gate electrode is integrated in the substrate, enabling the fabrication of micro-scale ion sensors for biomedical applications. The approach is versatile and can be extended to include numerous ion-selective transistors on a chip in order to meet the demand for simultaneous sensing of multiple ions.
Selective Ion Detection with Integrated Organic Electrochemical Transistors
Torricelli F.;
2021-01-01
Abstract
Accurate sensing of ion concentrations in body fluids is of importance to monitor cell functions, and any deviation of the concentration serves as a warning sign of pathophysiological conditions. Here, a fabrication approach for an integrated device consisting of two electrochemical transistors, capable of selective simultaneous detection between potassium and sodium ions in an analyte is demonstrated. A common in-plane gate electrode is integrated in the substrate, enabling the fabrication of micro-scale ion sensors for biomedical applications. The approach is versatile and can be extended to include numerous ion-selective transistors on a chip in order to meet the demand for simultaneous sensing of multiple ions.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
