Introduction: Spontaneous preterm birth in women with a twin pregnancy is one of the main causes of perinatal mortality and morbidity. Our aim was to review the perinatal outcome of asymptomatic twin pregnancies with a sonographic short cervical length during the second trimester treated with an ultrasound-indicated cerclage or cervical pessary. Material and methods: Retrospective study on asymptomatic twin pregnancies with a short cervix (≤ 25 mm) at transvaginal ultrasound examination during the second trimester treated with a cervical cerclage or pessary (2001-2017). The rate of preterm birth < 28, 32 and 34 weeks of gestation, neonatal mortality, neonatal morbidity and composite adverse neonatal outcome were compared in the groups of women treated with cerclage or pessary. Results: Seventy-four twin pregnancies underwent a cerclage while a cervical pessary was inserted in 34 women with twins at our Department: 36 women with an ultrasound-indicated cerclage and 20 with a pessary were included in the analysis. Median gestational age at delivery was higher in women treated with cerclage compared with those with pessary placement (P =.02) and the rate of preterm birth before 34 weeks of gestation was lower in the cerclage group (P =.03). Admissions to the Neonatal Intensive Care Unit were more frequent in pregnancies with pessary (P =.01), the length of admission was longer (P =.005) and composite adverse neonatal outcome occurred more often (P =.03) compared with the cerclage group. Conclusions: Ultrasound-indicated cerclage appears to reduce the rate of preterm birth before 34 weeks of gestation in asymptomatic twin pregnancies with a short cervix during the second trimester, and also the composite adverse neonatal outcome compared with pessary. © 2018 Nordic Federation of Societies of Obstetrics and Gynecology

The use of ultrasound-indicated cerclage or cervical pessary in asymptomatic twin pregnancies with a short cervix at midgestation

Fichera, Anna
Writing – Original Draft Preparation
;
Prefumo, Federico
Writing – Review & Editing
;
MAZZONI, GIORGIA
Writing – Original Draft Preparation
;
Sartori, Enrico
Writing – Original Draft Preparation
2019-01-01

Abstract

Introduction: Spontaneous preterm birth in women with a twin pregnancy is one of the main causes of perinatal mortality and morbidity. Our aim was to review the perinatal outcome of asymptomatic twin pregnancies with a sonographic short cervical length during the second trimester treated with an ultrasound-indicated cerclage or cervical pessary. Material and methods: Retrospective study on asymptomatic twin pregnancies with a short cervix (≤ 25 mm) at transvaginal ultrasound examination during the second trimester treated with a cervical cerclage or pessary (2001-2017). The rate of preterm birth < 28, 32 and 34 weeks of gestation, neonatal mortality, neonatal morbidity and composite adverse neonatal outcome were compared in the groups of women treated with cerclage or pessary. Results: Seventy-four twin pregnancies underwent a cerclage while a cervical pessary was inserted in 34 women with twins at our Department: 36 women with an ultrasound-indicated cerclage and 20 with a pessary were included in the analysis. Median gestational age at delivery was higher in women treated with cerclage compared with those with pessary placement (P =.02) and the rate of preterm birth before 34 weeks of gestation was lower in the cerclage group (P =.03). Admissions to the Neonatal Intensive Care Unit were more frequent in pregnancies with pessary (P =.01), the length of admission was longer (P =.005) and composite adverse neonatal outcome occurred more often (P =.03) compared with the cerclage group. Conclusions: Ultrasound-indicated cerclage appears to reduce the rate of preterm birth before 34 weeks of gestation in asymptomatic twin pregnancies with a short cervix during the second trimester, and also the composite adverse neonatal outcome compared with pessary. © 2018 Nordic Federation of Societies of Obstetrics and Gynecology
2019
Inglese
98
4
487
493
7
cerclage; cervical length; pessary; preterm birth; twin pregnancy; Obstetrics and Gynecology
http://obgyn.onlinelibrary.wiley.com/hub/journal/10.1111/(ISSN)1600-0412/
no
8
info:eu-repo/semantics/article
262
Fichera, Anna; Prefumo, Federico; Mazzoni, Giorgia; Molinaris, Valentina; Zanardini, Cristina; Fratelli, Nicola; Frusca, Tiziana; Sartori, Enrico...espandi
1 Contributo su Rivista::1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11379/514671
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