The selective adenosine A1 receptor antagonist rolofylline showed a neutral overall result on clinical outcomes in the PROTECT trial. However, we hypothesized that response to rolofylline treatment could be influenced by underlying clinical risk.

Risk-based evaluation of efficacy of rolofylline in patients hospitalized with acute heart failure - Post-hoc analysis of the PROTECT trial

Metra, Marco;
2016-01-01

Abstract

The selective adenosine A1 receptor antagonist rolofylline showed a neutral overall result on clinical outcomes in the PROTECT trial. However, we hypothesized that response to rolofylline treatment could be influenced by underlying clinical risk.
2016
Inglese
223
967
975
9
Acute heart failure; Heterogeneity of treatment effect; Multivariable risk; Rolofylline; STEPP; Subgroup analysis
16
info:eu-repo/semantics/article
262
Demissei, Biniyam G; Postmus, Douwe; Liu, Licette C Y; Cleland, John G; O'Connor, Christopher M; Metra, Marco; Ponikowski, Piotr; Teerlink, John R; Co...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11379/504471
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