The aim of this study was to evaluate the mutagenicity of several traditional detergents and that of newer more biodegradable detergents, by using a bacterial test (Ames test), a plant cell test (Allium cepa micronuclei test) and a human leucocyte test (Comet test). All tests were conducted using a wide range of doses (1-2000 mg/l). None of the examined detergents induced mutations in S.typhimurium. One traditional detergent showed a genotoxic effect with the A. cepa test, while all newer detergents and one traditional detergent were shown by the Comet test to be capable of inducing DNA damage.

Evaluation of the mutagenicity of detergents by tests on bacteria, plant cells and human leucocytes.[Studio della mutagenicità di formulati detergenti mediante test su batteri, cellule vegetali e leucociti umani]

FERETTI, Donatella;PEDRAZZANI, Roberta;CERETTI, Elisabetta;ZERBINI, ILARIA;BELOTTI, Caterina Elena;ALIAS, Carlotta;DONATO, Francesco;GELATTI, Umberto
2009-01-01

Abstract

The aim of this study was to evaluate the mutagenicity of several traditional detergents and that of newer more biodegradable detergents, by using a bacterial test (Ames test), a plant cell test (Allium cepa micronuclei test) and a human leucocyte test (Comet test). All tests were conducted using a wide range of doses (1-2000 mg/l). None of the examined detergents induced mutations in S.typhimurium. One traditional detergent showed a genotoxic effect with the A. cepa test, while all newer detergents and one traditional detergent were shown by the Comet test to be capable of inducing DNA damage.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11379/494439
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