Ruxolitinib is a JAK1 and JAK2 inhibitor, approved by the U.S. Food and Drug Administration (FDA) in November 2011, highly effective in the clinical management of myelofibrosis and associated complications (splenomegaly consequent to extramedullary hematopoiesis, cytopenias). We describe a case of Ruxolitinib-induced eruptive squamous cell carcinomas with keratoacanthoma-like features in a patient with myelofibrosis. A 74 year old woman was diagnosed with myelofibrosis in 2013 and was put on Ruxolinitib, without association of other immunosuppresive drugs. This article is protected by copyright. All rights reserved.

Eruptive squamous cell carcinomas with keratoacanthoma-like features in a patient treated with Ruxolitinib

CALZAVARA PINTON, Piergiacomo;MOGGIO, Erica;
2015-01-01

Abstract

Ruxolitinib is a JAK1 and JAK2 inhibitor, approved by the U.S. Food and Drug Administration (FDA) in November 2011, highly effective in the clinical management of myelofibrosis and associated complications (splenomegaly consequent to extramedullary hematopoiesis, cytopenias). We describe a case of Ruxolitinib-induced eruptive squamous cell carcinomas with keratoacanthoma-like features in a patient with myelofibrosis. A 74 year old woman was diagnosed with myelofibrosis in 2013 and was put on Ruxolinitib, without association of other immunosuppresive drugs. This article is protected by copyright. All rights reserved.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11379/462985
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