Whole-genome expression studies in the peripheral tissues of patients affected by schizophrenia (SCZ) can provide new insight into the molecular basis of the disorder and innovative biomarkers that may be of great utility in clinical practice. Recent evidence suggests that skin fibroblasts could represent a non-neural peripheral model useful for investigating molecular alterations in psychiatric disorders.
Altered gene expression in schizophrenia: findings from transcriptional signatures in fibroblasts and blood
CATTANE, Nadia;MINELLI, Alessandra;MILANESI, Elena;MAJ, Carlo;GENNARELLI, Massimo
2015-01-01
Abstract
Whole-genome expression studies in the peripheral tissues of patients affected by schizophrenia (SCZ) can provide new insight into the molecular basis of the disorder and innovative biomarkers that may be of great utility in clinical practice. Recent evidence suggests that skin fibroblasts could represent a non-neural peripheral model useful for investigating molecular alterations in psychiatric disorders.File in questo prodotto:
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