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We evaluated the expression of human trophoblast cell-surface marker (Trop-2) and the potential of hRS7, a humanized monoclonal anti-Trop-2 antibody, against treatment-refractory cervical cancer.

Cervical carcinomas overexpress human trophoblast cell-surface marker (Trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized monoclonal anti-Trop-2 antibody

BELLONE, Stefania;PECORELLI, Sergio;
2012-01-01

Abstract

We evaluated the expression of human trophoblast cell-surface marker (Trop-2) and the potential of hRS7, a humanized monoclonal anti-Trop-2 antibody, against treatment-refractory cervical cancer.
2012
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
2-s2.0-81855164839
WOS:000297329200032
Inglese
205
6
567.e1-7
21889762
Adenocarcinoma; Adult; Antibodies, Monoclonal; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Cell Line, Tumor; Complement System Proteins; Drug Resistance, Neoplasm; Drug Synergism; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulin G; Interleukin-2; Killer Cells, Natural; Real-Time Polymerase Chain Reaction; Tumor Markers, Biological; Uterine Cervical Neoplasms
11
info:eu-repo/semantics/article
262
Varughese, Joyce; Cocco, Emiliano; Bellone, Stefania; Ratner, Elena; Silasi, Dan Arin; Azodi, Masoud; Schwartz, Peter E; Rutherford, Thomas J; Buza, N...espandi
1 Contributo su Rivista::1.1 Articolo in rivista
none
1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11379/457298
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