Recent data suggest a possible involvement of Aquaporins (AQPs) in pain transmission. AQPs are small membrane channel proteins involved in osmoregulation and, to date, AQP1, AQP2, AQP3, AQP4, AQP5, AQP8 and AQP9 have been found in the nervous system. Nevertheless only AQP1, AQP2 and AQP4 seem to be involved in nociception.In this review, direct and indirect evidences of the role of AQPs in pain processing will be reported.
Aquaporins in sensory and pain transmission
BORSANI, Elisa
2010-01-01
Abstract
Recent data suggest a possible involvement of Aquaporins (AQPs) in pain transmission. AQPs are small membrane channel proteins involved in osmoregulation and, to date, AQP1, AQP2, AQP3, AQP4, AQP5, AQP8 and AQP9 have been found in the nervous system. Nevertheless only AQP1, AQP2 and AQP4 seem to be involved in nociception.In this review, direct and indirect evidences of the role of AQPs in pain processing will be reported.File in questo prodotto:
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Borsani E - v8 p122 Curr Neuropharmacol 2010.pdf
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