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Primary liver cancer in a high-incidence area in north Italy: etiological hypotheses arising from routinely collected data.

CHIESA, Roberta;DONATO, Francesco;PORTOLANI, Nazario;NARDI, Giuseppe
1995-01-01
1995
Ateneo di appartenenza
LS7_7 Surgery
LS7_6 Gene therapy, stem cell therapy, regenerative medicine
EUROPEAN JOURNAL OF EPIDEMIOLOGY
2-s2.0-0028978342
WOS:A1995RT82700011
Inglese
11
435
442
7
8549711
The incidence rate for primary liver cancer (PLC) was investigated in the Health Unit of Brescia (about 325,000 inhabitants), North Italy, in the 5-year period 1986-90, in order to ascertain whether there was a high risk for developing the disease in the area as suggested by mortality data. A total of 349 incident cases were observed (male: female ratio = 3.4: 1), of which 182 (52.1\%) were diagnosed through histology. The cumulative risk was about 5\% and 1\% in males and females, respectively. The crude incidence rates were 34.5/100,000 in males and 9.4/100,000 in females, and the age-standardized rates were the highest among all those observed in the 9 Italian areas covered by Cancer Registries. Although about half of the cases in males can be attributed to either chronic alcoholic disease or HBV infection or both, further research is needed to investigate the role of known risk factors for PLC in the Health Unit.
Adult; Age Distribution; Aged; 80 and over; Female; Humans; Incidence; Italy; Liver Neoplasms; Male; Middle Aged; Risk Factors; Sex Distribution; Survival Rate
6
info:eu-repo/semantics/article
262
Chiesa, Roberta; Donato, Francesco; Portolani, Nazario; M., Favret; V., Tomasoni; Nardi, Giuseppe
1 Contributo su Rivista::1.1 Articolo in rivista
none
1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11379/31007
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