[Smooth-muscle-cell tumors of the gastroenteric tract. A review of cases]

TIBERIO, Guido Alberto Massimo;GIULINI, Stefano Maria;TIBERIO, Giorgio
1997-01-01

1997
Altra università italiana
LS7_7 Surgery
LS7_6 Gene therapy, stem cell therapy, regenerative medicine
Italiano
52
1147
1155
8
Smooth muscle tumors of the gastrointestinal tract are difficult to evaluate and to stage. Twenty-four patients surgically treated during the last ten years have been evaluated using a TGM staging to identify the more rational criteria for the therapeutic choice. Six gastric leiomyomas, 1 ileal leiomyoma, 4 gastric leiomyosarcomas, 1 esophageal leiomyosarcoma, 4 ileal leiomyosarcomas, 2 rectal leiomyosarcomas and 6 gastric leiomyoblastomas were included. 62.5\% of cases presented acute clinical features. Preoperative histological diagnosis was adequate in 29\% of cases. We performed 7 excisions, 6 gastric subtotal resections, 3 total gastrectomies, 1 esophageal resection, 5 ileal resections, 2 rectal low anterior resection. Fourteen patients were staged I/II, 8 staged III and 2 staged IV. The overall median survival time was 27.5 months (56, 20 and 5 months concerning stage I/II, III and IV respectively; p < 0.01). In relation to T and G factors overall survival was statistically significant. TGM staging was highly significant to predict long-term survival. Radical surgical procedure was highly effective to guarantee long-term survival. Extended follow up is requested because recurrences after many years seem to be possible also with low histologic grade at first presentation.
Aged; 80 and over; Female; Follow-Up Studies; Gastrointestinal Neoplasms; Humans; Italy; Male; Middle Aged; Neoplasm Recurrence; Local; Neoplasm Staging; Smooth Muscle Tumor
6
info:eu-repo/semantics/article
262
O., Chiara; T., Canini; M., Segala; Tiberio, Guido Alberto Massimo; Giulini, Stefano Maria; Tiberio, Giorgio
1 Contributo su Rivista::1.1 Articolo in rivista
none
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11379/30884
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus 8
  • ???jsp.display-item.citation.isi??? ND
social impact