Sensory ganglionopathy is a rare form of neuropathy that may complicate Sjögren’s Syndrome (Mori et al., 2005). It results from lesions of the dorsal root ganglia, and spinal MRI may show poster- ior columns T2-weighted hyperintensity, expression of the retro- grade degeneration of the large afferent fibers in the posterior column (Lauria et al., 2000) and of the clinical severity of the neu- ronopathy (Mori et al., 2001). Clinically it presents with sensory ataxia, and sometimes upper limbs choreoathetotic movements. Cranial nerves may occasionally be involved, with trigeminal nerve being the most commonly affected. We describe a 66-year-old woman with Sjögren’s Syndrome with sensory ganglionopathy and severe trigeminal nerve involve- ment whose brain MRI revealed trigeminal nerve abnormalities consistent with the clinical picture.
MRI evidence of trigeminal sensory neuropathy in Sjogren's Syndrome.
GASPAROTTI, Roberto
2013-01-01
Abstract
Sensory ganglionopathy is a rare form of neuropathy that may complicate Sjögren’s Syndrome (Mori et al., 2005). It results from lesions of the dorsal root ganglia, and spinal MRI may show poster- ior columns T2-weighted hyperintensity, expression of the retro- grade degeneration of the large afferent fibers in the posterior column (Lauria et al., 2000) and of the clinical severity of the neu- ronopathy (Mori et al., 2001). Clinically it presents with sensory ataxia, and sometimes upper limbs choreoathetotic movements. Cranial nerves may occasionally be involved, with trigeminal nerve being the most commonly affected. We describe a 66-year-old woman with Sjögren’s Syndrome with sensory ganglionopathy and severe trigeminal nerve involve- ment whose brain MRI revealed trigeminal nerve abnormalities consistent with the clinical picture.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
