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Molecular therapies for hepatocellular carcinoma: silencing of urokinase by antisense and siRNA stable u-PA expression.

Molecular therapies for hepatocellular carcinoma: silencing of urokinase by antisense and siRNA stable u-PA expression.

DE PETRO, Giuseppina;SALVI, Alessandro;ARICI, Bruna;BARLATI, Sergio
2003-01-01

Abstract

Molecular therapies for hepatocellular carcinoma: silencing of urokinase by antisense and siRNA stable u-PA expression.
2003
Ateneo di appartenenza
LS2_6 Molecular genetics, reverse genetics and RNAi
TUMORI
sì
Nessuno
Inglese
Internazionale
STAMPA
vol 3 n 1
124
124
1
After demonstrating that uPA overexpression is an unfavourable prognostic factor for human HCC ( Cancer Res 1998 De Petro et al, Int J Cancer 2000, Tavian et al) we proposed and studied uPA overexpression as target for anti-cancer therapy of HCC. The technologies of antisense RNA and shRNA were both effective in silencing uPA in HCC.
stable expression of antisense RNA; shRNA uPA, HCC; molecular therapies.
Enti pubb. di ricerca ital.
info:eu-repo/semantics/article
266
none
4
1 Contributo su Rivista::1.5 Abstract in rivista
DE PETRO, Giuseppina; Salvi, Alessandro; Arici, Bruna; Barlati, Sergio
1.5 Abstract in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11379/161067
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