Probiotici ricombinanti e loro potenziale sulla salute umana

Recent evidence indicates that the segmented filamentous bacteria (BFS), Candidatus arthromitus, play a special role in several aspects of the immune system maturation, including T-cell responses, it is therefore particularly important reviewing the knowledge of these bacteria and their relation with the immune system and investigating their morphological aspects. In these organisms a developing form and a vegetative form can be distinguished. These different forms have different roles in the life cycle: the developing form allows a rapid growth of organisms, while the vegetative form allows the BFS adhesion to the follicular epithelium. We also paid particular attention to the way of interaction between the BFS and the epithelial cells of the terminal ileum, in order to better understand the unique relation between these bacteria and the immune system.