SPANO, Pier Franco
 Distribuzione geografica
Continente #
NA - Nord America 15.806
EU - Europa 9.877
AS - Asia 8.460
SA - Sud America 1.514
AF - Africa 155
OC - Oceania 31
Continente sconosciuto - Info sul continente non disponibili 22
Totale 35.865
Nazione #
US - Stati Uniti d'America 15.580
PL - Polonia 3.238
CN - Cina 3.202
SG - Singapore 2.653
UA - Ucraina 2.068
BR - Brasile 1.307
DE - Germania 1.126
HK - Hong Kong 902
IT - Italia 861
FI - Finlandia 543
GB - Regno Unito 535
VN - Vietnam 526
FR - Francia 484
IN - India 421
RU - Federazione Russa 348
TR - Turchia 324
IE - Irlanda 320
CA - Canada 126
BD - Bangladesh 94
SE - Svezia 89
BE - Belgio 66
AR - Argentina 64
ZA - Sudafrica 58
MX - Messico 57
ID - Indonesia 50
CZ - Repubblica Ceca 41
EC - Ecuador 38
IQ - Iraq 38
NL - Olanda 36
IR - Iran 35
KR - Corea 35
ES - Italia 29
AU - Australia 25
KE - Kenya 24
UZ - Uzbekistan 24
JP - Giappone 23
PK - Pakistan 22
CH - Svizzera 21
EU - Europa 21
PY - Paraguay 20
VE - Venezuela 20
IL - Israele 18
MA - Marocco 18
MU - Mauritius 18
AT - Austria 17
CO - Colombia 17
CL - Cile 15
EG - Egitto 14
UY - Uruguay 14
SA - Arabia Saudita 12
JO - Giordania 10
KZ - Kazakistan 10
PE - Perù 10
ET - Etiopia 9
AZ - Azerbaigian 8
OM - Oman 8
TT - Trinidad e Tobago 8
BG - Bulgaria 7
BO - Bolivia 7
SK - Slovacchia (Repubblica Slovacca) 7
JM - Giamaica 6
PS - Palestinian Territory 6
RO - Romania 6
AE - Emirati Arabi Uniti 5
CR - Costa Rica 5
PA - Panama 5
TN - Tunisia 5
DZ - Algeria 4
EE - Estonia 4
GT - Guatemala 4
HN - Honduras 4
LT - Lituania 4
NP - Nepal 4
NZ - Nuova Zelanda 4
PT - Portogallo 4
AL - Albania 3
AM - Armenia 3
BA - Bosnia-Erzegovina 3
DO - Repubblica Dominicana 3
LV - Lettonia 3
RS - Serbia 3
TW - Taiwan 3
BH - Bahrain 2
CY - Cipro 2
GD - Grenada 2
GE - Georgia 2
GR - Grecia 2
GY - Guiana 2
KG - Kirghizistan 2
LK - Sri Lanka 2
MD - Moldavia 2
MK - Macedonia 2
PH - Filippine 2
SV - El Salvador 2
TH - Thailandia 2
TJ - Tagikistan 2
TM - Turkmenistan 2
AO - Angola 1
BB - Barbados 1
BN - Brunei Darussalam 1
Totale 35.845
Città #
Warsaw 3.234
Fairfield 1.716
Woodbridge 1.712
Jacksonville 1.484
Singapore 1.219
Ashburn 1.207
Houston 1.013
Hong Kong 900
Ann Arbor 831
Cambridge 721
Chandler 719
Seattle 663
Wilmington 657
Beijing 594
Princeton 588
Nanjing 572
Dearborn 406
Dublin 318
Brescia 311
New York 306
Istanbul 264
Los Angeles 261
Helsinki 229
Nanchang 206
The Dalles 190
Des Moines 162
Shenyang 162
Munich 145
Pune 141
Ho Chi Minh City 140
Tianjin 140
Buffalo 128
Hebei 126
Changsha 125
Jinan 121
São Paulo 108
Moscow 105
Dong Ket 100
Lancaster 98
Milan 97
San Diego 84
Hanoi 83
Shanghai 83
San Francisco 81
Jiaxing 80
Redondo Beach 79
Kunming 72
London 66
Brussels 64
Dallas 62
Chicago 59
Santa Clara 54
Toronto 51
Verona 50
Hangzhou 48
Turku 47
Ningbo 44
Rio de Janeiro 43
Zhengzhou 42
Guangzhou 38
Taizhou 38
Brooklyn 35
Phoenix 35
Augusta 33
Denver 33
Johannesburg 32
San Mateo 31
Haikou 30
Jakarta 30
Ardabil 29
Boardman 29
Council Bluffs 29
Lanzhou 29
Brasília 28
Brno 28
Montreal 28
Monmouth Junction 27
Orem 27
Kocaeli 26
Belo Horizonte 25
Norwalk 25
Boston 24
Leawood 24
Mexico City 24
Rome 24
Manchester 23
Poplar 23
Tashkent 23
Changchun 22
Atlanta 21
Haiphong 21
Tokyo 21
Dhaka 20
Nairobi 20
Orange 20
Frankfurt am Main 19
Porto Alegre 18
Fuzhou 17
Basel 16
Chennai 16
Totale 24.472
Nome #
CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid 358
Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation 338
PEA and luteolin synergistically reduce mast cell-mediated toxicity and elicit neuroprotection in cell-based models of brain ischemia 312
Glutamatergic neurons induce expression of functional glutamatergic synapses in primary myotubes. 311
Glutamatergic Reinnervation and Assembly of Glutamatergic Synapses in Adult Rat Skeletal Muscle Occurs at Cholinergic Endplates 303
Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling 299
1B/(-)IRE DMT1 Expression during Brain Ischemia Contributes to Cell Death Mediated by NF-κB/RelA Acetylation at Lys310 296
Redistribution of DAT/α-synuclein complexes visualized by “in situ” proximity ligation assay in transgenic mice modelling early Parkinson’s disease 295
Glutamatergic reinnervation through peripheral nerve graft dictates assembly of glutamatergic synapses at rat skeletal muscle 283
GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity 282
Priming of cultured neurons with sabeluzole results in long-lasting inhibition of neurotoxin-induced tau expression and cell death. 277
NF-κB and epigenetic mechanisms as integrative regulators of brain resilience to anoxic stress. 276
Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window. 272
NF-κB in Innate Neuroprotection and Age-Related Neurodegenerative Diseases 270
Late-onset Parkinsonism in NFκB/c-Rel-deficient mice. 256
The End Is the Beginning: Parkinson's Disease in the Light of Brain Imaging 256
Mild inflammatory profile without gliosis in the c-rel deficient mouse modeling a late-onset parkinsonism 255
The Contribution of -Synuclein Spreading to Parkinson’s Disease Synaptopathy 249
Synergistic association of valproate and resveratrol reduces brain injury in ischemic stroke 245
Nicotine-induced structural plasticity in mesencephalic dopaminergic neurons is mediated by dopamine d3 receptors and akt-mtorc1 signaling 234
The "in situ" proximity ligation assay to probe protein-protein interactions in intact tissues 212
Mitochondria and alpha-synuclein: Friends or foes in the pathogenesis of Parkinson's disease? 200
An Integrated Approach for a Structural and Functional Evaluation of Biosimilars: Implications for Erythropoietin 193
Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains 193
Role of Dopamine D2/D3 Receptors in Development, Plasticity, and Neuroprotection in Human iPSC-Derived Midbrain Dopaminergic Neurons 191
Chapter 24 NF-KappaB Dimers in the Regulation of Neuronal Survival 189
NUOVO IMPIEGO TERAPEUTICO PREVENTIVO DELLA SUBUNITA' C-REL DELLA PROTEINA NF-KAPPAB E NUOVO IMPIEGO DI UN ANIMALE TRASGENICO NON UMANO CHE PORTA LA DELEZIONE DEL GENE C-REL (C-REL-/-) 188
The gamma-Secretase Modulator CHF5074 Reduces the Accumulation of Native Hyperphosphorylated Tau in a Transgenic Mouse Model of Alzheimer's Disease 187
Targeting IKK2 by pharmacological inhibitor AS602868 prevents excitotoxic injury to neurons and oligodendrocytes. 186
c-Rel deficient mice, a mouse model of "spreading" PD-like pathology. 186
Spinal cord mGlu1a receptors - Possible target for amyotrophic lateral sclerosis therapy 181
Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2/D3 receptor activation 181
Inhibition of Survivin Is Associated with Zoledronic Acid-induced Apoptosis of Prostate Cancer Cells 178
Post-ischemic brain damage: NF-kappaB dimer heterogeneity as a molecular determinant of neuron vulnerability 177
NF-kappaB p50/RelA and c-Rel-containing dimers: opposite regulators of neuron vulnerability to ischaemia. 176
Bim and Noxa are candidates to mediate the deleterious effect of the NF-kappa B subunit RelA in cerebral ischemia. 173
Different muscarinic receptor subtypes modulate proliferation of primary human detrusor smooth muscle cells via Akt/PI3K and map kinases. 171
Identification and characterization of a kappa B/Rel binding site in the regulatory region of the amyloid precursor protein gene. 168
Age-related changes of enkephalin in rat spinal cord 167
The proximity ligation assay: an high throughput technique for protein analysis in neuroscience 166
Expression of functional NR1/NR2B-type NMDA receptors in neuronally differentiated SK-N-SH human cell line 162
α-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons 162
A new pharmacological approach to the facilitation of acetylcholine transmission. 161
Depletion of Progranulin Reduces GluN2B-Containing NMDA Receptor Density, Tau Phosphorylation, and Dendritic Arborization in Mouse Primary Cortical Neurons 159
Targeting of Disordered Proteins by Small Molecules in Neurodegenerative Diseases 159
From α-synuclein to synaptic dysfunctions: new insights into the pathophysiology of Parkinson's disease 157
EXACERBATED AGE-DEPENDENT LOSS OF NIGRAL DOPAMINERGIC NEURONS IN NF-KAPPAB C-REL -/- MICE 156
Cellular mechanisms for neurotensin receptor-mediated release of prolactin. 152
Activation of NF-kappaB p65/c-Rel dimer is associated with neuroprotection elicited by mGlu5 receptor agonists against MPP(+) toxicity in SK-N-SH cells. 152
c-Rel deficient mice, a mouse model of “spreading” PD-like pathology 152
The gamma-secretase modulator CHF5074 elicits neuroprotection and increases histone acetylation in primary cortical neurons exposed to oxygen glucose deprivation 151
Alpha1 adrenoceptor subtypes in human urinary bladder: sex and regional comparison. 150
Nerve growth factor suppresses the transforming phenotype of human prolactinomas 149
Synapsin III alterations in Parkinson's disease 149
ALPHA-SYNUCLEIN MODULATES SYNAPSIN III IN NIGROSTRIATAL DOPAMINERGIC NEURONS: IMPLICATIONS FOR PARKINSON'S DISEASE 148
Structural plasticity in mesencephalic dopaminergic neurons produced by drugs of abuse: critical role of BDNF and dopamine 148
Mitochondrial Dysfunction and Alpha-Synuclein Synaptic Pathology in Parkinson’s Disease: Who’s on First? 148
Clozapine-induced alteration of glucose homeostasis in the rat: the contribution of hypothalamic-pituitary-adrenal axis activation 146
Acute scopolamine treatment decreases dopamine metabolism in rat hippocampus and frontal cortex 145
Degenerazione età –dipendente dei neuroni dopaminergici della sostanza nera nei topi NF-kappaB cRel 145
Computational and functional analysis of biopharmaceutical drugs in zebrafish: Erythropoietin as a test model 145
Synergistic association of valproate and resveratrol reduces brain injury in ischemic stroke. 145
SYNERGIC ROLE OF RESVERATROL AND HDACi MS-275 IN NEUROPROTECTION 143
The miR-21/PTEN/Akt signaling pathway is involved in the anti-tumoral effects of zoledronic acid in human breast cancer cell lines 141
mGluR5 metabotropic glutamate receptor distribution in rat and human spinal cord: a developmental study. 140
Induction of tumour-suppressor phosphoprotein p53 in the apoptosis of cultured rat cerebellar neurones triggered by excitatory amino acids. 140
Nerve growth factor in the anterior pituitary: localization in mammotroph cells and co-secretion with prolactin by a dopamine-regulated mechanism 140
Acetylation of NF-kappaB p50/RelA and histones in the epigenetic regulation of pro-apoptotic transcription: a neuroprotective target in brain ischemia 140
Identification of novel alternatively-spliced mRNA isoforms of metabotropic glutamate receptor 6 gene in rat and human retina. 139
Opposing roles for D-1 and D-2 dopamine receptors in the regulation of lower esophageal sphincter motility in the rat. 139
Differential effects of caffeine on dihydroxyphenylacetic acid concentrations in various rat brain dopaminergic structures 137
Metabotropic glutamate receptor mRNA expression in rat spinal cord 137
Soluble interleukin-6 (IL-6) receptor/IL-6 fusion protein enhances in vitro differentiation of purified rat oligodendroglial lineage cells. 136
Involvement of Synapsin III in the onset of alpha-synuclein synaptic pathology in Parkinson’s disease 136
Tau protein immunolocalization in fetal and adult human spinal cord. 135
Epidermal growth factor induces the functional expression of dopamine receptors in the GH3 cell line 135
Ketamine enhances structural plasticity in mouse mesencephalic and human iPSC-derived dopaminergic neurons via AMPAR-driven BDNF and mTOR signaling 134
Opposing regulation of tau protein levels by ionotropic and metabotropic glutamate receptors in human NT2 neurons 132
Nerve growth factor directs differentiation of the bipotential cell line GH-3 into the mammotroph phenotype 132
Dopamine receptors are present in rat and human esophagus 132
Inhibition of IκBα phosphorylation prevents glutamate-induced NF-κB activation and neuronal cell death 132
Gene expression profile activated by the chemokine CCL5/RANTES in human neuronal cells 130
An in vitro method of diagnosing Parkinson's disease 130
Differential gene expression of cholinergic muscarinic receptor subtypes in male and female normal human urinary bladder. 130
SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease. 128
Nerve growth factor signaling in prostate health and disease. 128
Sex-related variations in serum nerve growth factor concentration in humans. 127
Dimerization of dopamine D1 and D3 receptors in the regulation of striatal function 127
Chronic lead exposure alters dopaminergic mechanisms in rat pituitary 127
Evidence for the presence of D1 and D2 dopamine receptors in the rat adrenal cortex 126
Synapsin III Alteration in Parkinson's disease 126
The neurobiology of dopamine receptors: evolution from the dual concept to heterodimer complexes 125
A direct interaction between dopamine D1 receptor and phosphatase Shp-2 triggers Erk activation in striatal neurons 125
Identification of D2 dopaminergic receptors in bovine adrenal cortex. 125
A soluble interleukin-6 (IL6) recepetor/IL6 fusion protein enhances the in vitro differentiation of purified rat oligodendroglial lineage cells 125
The tyrosine phosphatase Shp-2 interacts with the dopamine D(1) receptor and triggers D(1) -mediated Erk signaling in striatal neurons. 124
Chronic lead exposure differentially affects dopamine transport in rat striatum and nucleus accumbens. 124
Different neurotransmitter systems are involved in the development of esophageal achalasia 123
The NMDA/D1 receptor complex as a new target in drug development 123
Detection of muscarinic receptor subtypes in human urinary bladder mucosa: Age and gender-dependent modifications 123
Totale 17.667
Categoria #
all - tutte 163.927
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 163.927


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20212.877 0 0 0 0 0 489 170 532 681 321 506 178
2021/20222.375 169 525 34 90 26 71 138 137 116 310 208 551
2022/20232.035 333 35 68 175 180 584 0 192 294 26 70 78
2023/20241.962 127 36 159 126 108 461 72 84 400 31 40 318
2024/20254.772 29 57 36 612 530 335 492 122 650 309 981 619
2025/20265.476 862 1.213 647 1.353 871 530 0 0 0 0 0 0
Totale 36.773