SPANO, Pier Franco
 Distribuzione geografica
Continente #
NA - Nord America 13.560
EU - Europa 9.223
AS - Asia 4.757
OC - Oceania 29
AF - Africa 23
SA - Sud America 22
Continente sconosciuto - Info sul continente non disponibili 21
Totale 27.635
Nazione #
US - Stati Uniti d'America 13.484
PL - Polonia 3.200
CN - Cina 2.346
UA - Ucraina 2.033
DE - Germania 986
IT - Italia 786
HK - Hong Kong 778
SG - Singapore 772
FI - Finlandia 488
FR - Francia 470
GB - Regno Unito 416
IN - India 329
IE - Irlanda 314
TR - Turchia 302
RU - Federazione Russa 282
VN - Vietnam 102
SE - Svezia 74
CA - Canada 69
BE - Belgio 66
CZ - Repubblica Ceca 37
KR - Corea 34
IR - Iran 33
ID - Indonesia 29
AU - Australia 25
EU - Europa 21
NL - Olanda 19
MU - Mauritius 18
CH - Svizzera 17
CL - Cile 9
ES - Italia 9
BR - Brasile 8
IL - Israele 6
MX - Messico 5
RO - Romania 5
JP - Giappone 4
NZ - Nuova Zelanda 4
TW - Taiwan 3
AR - Argentina 2
BA - Bosnia-Erzegovina 2
BD - Bangladesh 2
BG - Bulgaria 2
BO - Bolivia 2
EE - Estonia 2
ET - Etiopia 2
GE - Georgia 2
KZ - Kazakistan 2
LT - Lituania 2
MK - Macedonia 2
PK - Pakistan 2
PT - Portogallo 2
SK - Slovacchia (Repubblica Slovacca) 2
TH - Thailandia 2
AM - Armenia 1
AT - Austria 1
AZ - Azerbaigian 1
BZ - Belize 1
EG - Egitto 1
GR - Grecia 1
HR - Croazia 1
HU - Ungheria 1
JO - Giordania 1
KG - Kirghizistan 1
LU - Lussemburgo 1
LV - Lettonia 1
OM - Oman 1
PA - Panama 1
PE - Perù 1
SA - Arabia Saudita 1
SI - Slovenia 1
SL - Sierra Leone 1
TJ - Tagikistan 1
TM - Turkmenistan 1
UZ - Uzbekistan 1
ZA - Sudafrica 1
Totale 27.635
Città #
Warsaw 3.200
Fairfield 1.716
Woodbridge 1.712
Jacksonville 1.480
Houston 1.002
Ashburn 921
Ann Arbor 831
Hong Kong 776
Cambridge 721
Chandler 719
Singapore 659
Wilmington 655
Seattle 648
Princeton 588
Nanjing 572
Dearborn 406
Dublin 312
Beijing 304
Brescia 302
Istanbul 261
Helsinki 221
New York 206
Nanchang 204
Shenyang 160
Des Moines 143
Pune 138
Tianjin 131
Hebei 126
Changsha 120
Jinan 116
Dong Ket 100
Moscow 100
Lancaster 97
Milan 84
San Diego 84
Jiaxing 79
Shanghai 73
Kunming 70
Brussels 64
Verona 50
Hangzhou 47
London 46
Los Angeles 45
Ningbo 44
Munich 43
Toronto 43
Taizhou 38
Zhengzhou 34
San Francisco 33
San Mateo 31
Haikou 30
Ardabil 29
Augusta 29
Boardman 29
Jakarta 29
Brno 28
Lanzhou 28
Monmouth Junction 27
Kocaeli 26
Guangzhou 25
Leawood 24
Orange 20
Changchun 19
Norwalk 18
Rome 18
Fuzhou 17
Basel 16
Ottawa 15
Hefei 14
Kilburn 14
Phoenix 14
San Donà Di Piave 14
Romola 12
Taiyuan 11
Canberra 9
Santa Clara 9
Madrid 8
Nürnberg 8
Teramo 8
Auburn Hills 7
Melbourne 7
New Bedfont 7
Olomouc 7
Redwood City 7
Chicago 6
Seoul 6
Vicenza 6
Acton 5
Bergamo 5
Bologna 5
Chions 5
Clifton 5
Hanover 5
Mumbai 5
Redmond 5
Sydney 5
Chiswick 4
Dallas 4
Falkenstein 4
Fulda 4
Totale 21.217
Nome #
CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid 312
Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation 278
PEA and luteolin synergistically reduce mast cell-mediated toxicity and elicit neuroprotection in cell-based models of brain ischemia 269
Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling 267
Glutamatergic neurons induce expression of functional glutamatergic synapses in primary myotubes. 265
Redistribution of DAT/α-synuclein complexes visualized by “in situ” proximity ligation assay in transgenic mice modelling early Parkinson’s disease 257
Glutamatergic Reinnervation and Assembly of Glutamatergic Synapses in Adult Rat Skeletal Muscle Occurs at Cholinergic Endplates 255
Glutamatergic reinnervation through peripheral nerve graft dictates assembly of glutamatergic synapses at rat skeletal muscle 251
1B/(-)IRE DMT1 Expression during Brain Ischemia Contributes to Cell Death Mediated by NF-κB/RelA Acetylation at Lys310 245
GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity 239
NF-κB in Innate Neuroprotection and Age-Related Neurodegenerative Diseases 233
The End Is the Beginning: Parkinson's Disease in the Light of Brain Imaging 233
The Contribution of -Synuclein Spreading to Parkinson’s Disease Synaptopathy 231
Priming of cultured neurons with sabeluzole results in long-lasting inhibition of neurotoxin-induced tau expression and cell death. 229
NF-κB and epigenetic mechanisms as integrative regulators of brain resilience to anoxic stress. 228
Late-onset Parkinsonism in NFκB/c-Rel-deficient mice. 224
Mild inflammatory profile without gliosis in the c-rel deficient mouse modeling a late-onset parkinsonism 220
Synergistic association of valproate and resveratrol reduces brain injury in ischemic stroke 220
Nicotine-induced structural plasticity in mesencephalic dopaminergic neurons is mediated by dopamine d3 receptors and akt-mtorc1 signaling 219
Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window. 218
Mitochondria and alpha-synuclein: Friends or foes in the pathogenesis of Parkinson's disease? 180
The "in situ" proximity ligation assay to probe protein-protein interactions in intact tissues 166
NUOVO IMPIEGO TERAPEUTICO PREVENTIVO DELLA SUBUNITA' C-REL DELLA PROTEINA NF-KAPPAB E NUOVO IMPIEGO DI UN ANIMALE TRASGENICO NON UMANO CHE PORTA LA DELEZIONE DEL GENE C-REL (C-REL-/-) 166
Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains 160
The gamma-Secretase Modulator CHF5074 Reduces the Accumulation of Native Hyperphosphorylated Tau in a Transgenic Mouse Model of Alzheimer's Disease 159
Role of Dopamine D2/D3 Receptors in Development, Plasticity, and Neuroprotection in Human iPSC-Derived Midbrain Dopaminergic Neurons 159
Targeting IKK2 by pharmacological inhibitor AS602868 prevents excitotoxic injury to neurons and oligodendrocytes. 153
Spinal cord mGlu1a receptors - Possible target for amyotrophic lateral sclerosis therapy 152
Post-ischemic brain damage: NF-kappaB dimer heterogeneity as a molecular determinant of neuron vulnerability 151
c-Rel deficient mice, a mouse model of "spreading" PD-like pathology. 150
Bim and Noxa are candidates to mediate the deleterious effect of the NF-kappa B subunit RelA in cerebral ischemia. 148
NF-kappaB p50/RelA and c-Rel-containing dimers: opposite regulators of neuron vulnerability to ischaemia. 146
Different muscarinic receptor subtypes modulate proliferation of primary human detrusor smooth muscle cells via Akt/PI3K and map kinases. 140
Targeting of Disordered Proteins by Small Molecules in Neurodegenerative Diseases 139
Chapter 24 NF-KappaB Dimers in the Regulation of Neuronal Survival 139
An Integrated Approach for a Structural and Functional Evaluation of Biosimilars: Implications for Erythropoietin 138
Inhibition of Survivin Is Associated with Zoledronic Acid-induced Apoptosis of Prostate Cancer Cells 137
Age-related changes of enkephalin in rat spinal cord 130
Identification and characterization of a kappa B/Rel binding site in the regulatory region of the amyloid precursor protein gene. 129
Expression of functional NR1/NR2B-type NMDA receptors in neuronally differentiated SK-N-SH human cell line 128
Structural plasticity in mesencephalic dopaminergic neurons produced by drugs of abuse: critical role of BDNF and dopamine 128
Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2/D3 receptor activation 127
Cellular mechanisms for neurotensin receptor-mediated release of prolactin. 127
A new pharmacological approach to the facilitation of acetylcholine transmission. 124
mGluR5 metabotropic glutamate receptor distribution in rat and human spinal cord: a developmental study. 123
The proximity ligation assay: an high throughput technique for protein analysis in neuroscience 121
Induction of tumour-suppressor phosphoprotein p53 in the apoptosis of cultured rat cerebellar neurones triggered by excitatory amino acids. 117
Differential effects of caffeine on dihydroxyphenylacetic acid concentrations in various rat brain dopaminergic structures 117
From α-synuclein to synaptic dysfunctions: new insights into the pathophysiology of Parkinson's disease 117
Synapsin III alterations in Parkinson's disease 115
Tau protein immunolocalization in fetal and adult human spinal cord. 114
The gamma-secretase modulator CHF5074 elicits neuroprotection and increases histone acetylation in primary cortical neurons exposed to oxygen glucose deprivation 113
Differential gene expression of cholinergic muscarinic receptor subtypes in male and female normal human urinary bladder. 113
Nerve growth factor suppresses the transforming phenotype of human prolactinomas 112
Acute scopolamine treatment decreases dopamine metabolism in rat hippocampus and frontal cortex 112
Identification of novel alternatively-spliced mRNA isoforms of metabotropic glutamate receptor 6 gene in rat and human retina. 112
Clozapine-induced alteration of glucose homeostasis in the rat: the contribution of hypothalamic-pituitary-adrenal axis activation 112
SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease. 112
Dopamine receptors are present in rat and human esophagus 112
The tyrosine phosphatase Shp-2 interacts with the dopamine D(1) receptor and triggers D(1) -mediated Erk signaling in striatal neurons. 112
Depletion of Progranulin Reduces GluN2B-Containing NMDA Receptor Density, Tau Phosphorylation, and Dendritic Arborization in Mouse Primary Cortical Neurons 112
Synergistic association of valproate and resveratrol reduces brain injury in ischemic stroke. 112
Alpha1 adrenoceptor subtypes in human urinary bladder: sex and regional comparison. 111
Metabotropic glutamate receptor mRNA expression in rat spinal cord 111
Mitochondrial Dysfunction and Alpha-Synuclein Synaptic Pathology in Parkinson’s Disease: Who’s on First? 111
Computational and functional analysis of biopharmaceutical drugs in zebrafish: Erythropoietin as a test model 111
c-Rel deficient mice, a mouse model of “spreading” PD-like pathology 111
SYNERGIC ROLE OF RESVERATROL AND HDACi MS-275 IN NEUROPROTECTION 110
Chronic lead exposure alters dopaminergic mechanisms in rat pituitary 110
Vasoactive Intestinal Polypeptide (VIP) selectively stimulates prolactin release in healthy women 110
EXACERBATED AGE-DEPENDENT LOSS OF NIGRAL DOPAMINERGIC NEURONS IN NF-KAPPAB C-REL -/- MICE 110
Opposing regulation of tau protein levels by ionotropic and metabotropic glutamate receptors in human NT2 neurons 109
Opposing roles for D-1 and D-2 dopamine receptors in the regulation of lower esophageal sphincter motility in the rat. 109
The neurobiology of dopamine receptors: evolution from the dual concept to heterodimer complexes 109
Chronic lead exposure differentially affects dopamine transport in rat striatum and nucleus accumbens. 109
The miR-21/PTEN/Akt signaling pathway is involved in the anti-tumoral effects of zoledronic acid in human breast cancer cell lines 109
Sex-related variations in serum nerve growth factor concentration in humans. 108
Identification of D2 dopaminergic receptors in bovine adrenal cortex. 108
Evidence for the presence of D1 and D2 dopamine receptors in the rat adrenal cortex 108
Post-synaptic D1 and D2 dopamine receptors are present in rabbit renal and mesenteric arteries 108
α-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons 108
Nerve growth factor in the anterior pituitary: localization in mammotroph cells and co-secretion with prolactin by a dopamine-regulated mechanism 107
Effect of lead exposure on dopaminergic receptors in rat striatum and nucleus accumbens 107
Dimerization of dopamine D1 and D3 receptors in the regulation of striatal function 105
Ketamine enhances structural plasticity in mouse mesencephalic and human iPSC-derived dopaminergic neurons via AMPAR-driven BDNF and mTOR signaling 105
Nerve growth factor directs differentiation of the bipotential cell line GH-3 into the mammotroph phenotype 104
Prevention of neuron and oligodendrocyte degeneration by interleukin-6 (IL-6) and IL-6 receptor/IL-6 fusion protein in organotypic hippocampal slices 104
Clinical Outcome After Extended Endovascular Recanalization in Buerger's Disease in 20 Consecutive Cases. 104
Different neurotransmitter systems are involved in the development of esophageal achalasia 103
Evidence for the presence of both D-1 and D-2 dopamine receptors in human esophagus. 103
Epidermal growth factor induces the functional expression of dopamine receptors in the GH3 cell line 103
The NMDA/D1 receptor complex as a new target in drug development 103
Degenerazione età –dipendente dei neuroni dopaminergici della sostanza nera nei topi NF-kappaB cRel 103
Inhibition of IκBα phosphorylation prevents glutamate-induced NF-κB activation and neuronal cell death 102
Activation of NF-kappaB p65/c-Rel dimer is associated with neuroprotection elicited by mGlu5 receptor agonists against MPP(+) toxicity in SK-N-SH cells. 102
Nerve growth factor suppresses the tumoral phenotype of human prolactinomas 101
The inhibitor of IkappaBalpha phosphorylation BAY 11-7082 prevents NMDA neurotoxicity in mouse hippocampal slices. 101
Selective disarrangement of the rostral telencephalic cholinergic system in heterozygous reeler mice. 101
Nerve growth factor signaling in prostate health and disease. 101
Gene expression profile activated by the chemokine CCL5/RANTES in human neuronal cells 100
Totale 14.466
Categoria #
all - tutte 127.789
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 127.789


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20203.988 0 0 0 0 0 0 780 870 487 1.102 303 446
2020/20214.303 108 520 106 542 150 489 170 532 681 321 506 178
2021/20222.375 169 525 34 90 26 71 138 137 116 310 208 551
2022/20232.035 333 35 68 175 180 584 0 192 294 26 70 78
2023/20241.962 127 36 159 126 108 461 72 84 400 31 40 318
2024/20252.018 29 57 36 612 530 335 419 0 0 0 0 0
Totale 28.543