SPANO, Pier Franco
 Distribuzione geografica
Continente #
NA - Nord America 20.806
EU - Europa 10.769
AS - Asia 9.536
SA - Sud America 1.683
Continente sconosciuto - Info sul continente non disponibili 943
AF - Africa 222
OC - Oceania 34
Totale 43.993
Nazione #
US - Stati Uniti d'America 20.282
CN - Cina 3.510
PL - Polonia 3.245
SG - Singapore 3.040
UA - Ucraina 2.079
BR - Brasile 1.397
DE - Germania 1.168
IT - Italia 1.118
HK - Hong Kong 934
FR - Francia 774
FI - Finlandia 650
GB - Regno Unito 601
VN - Vietnam 591
IN - India 474
RU - Federazione Russa 393
TR - Turchia 327
IE - Irlanda 324
CA - Canada 250
BD - Bangladesh 185
SE - Svezia 95
AR - Argentina 81
MX - Messico 74
BE - Belgio 73
ID - Indonesia 66
ZA - Sudafrica 64
IQ - Iraq 57
EC - Ecuador 50
NL - Olanda 49
CZ - Repubblica Ceca 41
ES - Italia 38
IL - Israele 38
JP - Giappone 38
KR - Corea 37
PK - Pakistan 37
IR - Iran 35
CR - Costa Rica 34
CO - Colombia 33
VE - Venezuela 33
TT - Trinidad e Tobago 31
CL - Cile 30
KE - Kenya 28
AU - Australia 27
UZ - Uzbekistan 27
CH - Svizzera 23
EU - Europa 21
GT - Guatemala 21
MA - Marocco 21
PY - Paraguay 21
NG - Nigeria 20
AT - Austria 19
HN - Honduras 19
JM - Giamaica 19
MU - Mauritius 18
EG - Egitto 17
NI - Nicaragua 16
SA - Arabia Saudita 16
SC - Seychelles 15
UY - Uruguay 15
GP - Guadalupe 14
KZ - Kazakistan 13
SV - El Salvador 13
JO - Giordania 12
PE - Perù 12
TN - Tunisia 12
CW - ???statistics.table.value.countryCode.CW??? 11
ET - Etiopia 11
PR - Porto Rico 10
BG - Bulgaria 9
BO - Bolivia 9
NP - Nepal 9
OM - Oman 9
SK - Slovacchia (Repubblica Slovacca) 9
AZ - Azerbaigian 8
MY - Malesia 8
PH - Filippine 8
RO - Romania 8
DZ - Algeria 7
EE - Estonia 7
PS - Palestinian Territory 7
AE - Emirati Arabi Uniti 6
DO - Repubblica Dominicana 6
AL - Albania 5
AM - Armenia 5
BA - Bosnia-Erzegovina 5
BH - Bahrain 5
LT - Lituania 5
NZ - Nuova Zelanda 5
PA - Panama 5
PT - Portogallo 5
TW - Taiwan 5
DK - Danimarca 4
LV - Lettonia 4
RS - Serbia 4
TH - Thailandia 4
BB - Barbados 3
GD - Grenada 3
GE - Georgia 3
HR - Croazia 3
LK - Sri Lanka 3
MD - Moldavia 3
Totale 43.036
Città #
Warsaw 3.235
Ashburn 1.936
Fairfield 1.717
Woodbridge 1.712
Singapore 1.559
Jacksonville 1.488
Houston 1.023
San Jose 985
Hong Kong 932
Ann Arbor 831
Cambridge 721
Chandler 719
Council Bluffs 687
Seattle 671
Wilmington 657
Beijing 620
Princeton 593
Nanjing 573
The Dalles 500
Dearborn 406
New York 358
Helsinki 336
Dublin 323
Brescia 318
Los Angeles 299
Columbus 279
Istanbul 265
Lauterbourg 263
Nanchang 206
Des Moines 165
Shenyang 162
Ho Chi Minh City 161
Munich 148
São Paulo 147
Buffalo 141
Pune 141
Milan 140
Tianjin 140
Hebei 126
Changsha 125
Jinan 121
Santa Clara 117
Dallas 110
Moscow 107
San Francisco 101
Dong Ket 100
Lancaster 100
Chicago 95
Hanoi 95
Shanghai 88
San Diego 87
Jiaxing 80
Redondo Beach 79
London 78
Toronto 77
Kunming 72
Phoenix 71
Orem 70
Brussels 68
Montreal 62
Rome 60
Hangzhou 53
Verona 53
Brooklyn 50
Turku 47
Ningbo 46
Rio de Janeiro 45
Zhengzhou 42
North Bergen 41
Atlanta 40
Frankfurt am Main 40
Guangzhou 40
Denver 38
Taizhou 38
Boardman 36
Manchester 35
Augusta 34
Chennai 34
Johannesburg 34
Tokyo 34
Jakarta 33
San Mateo 31
Brasília 30
Haikou 30
San José 30
Ardabil 29
Boston 29
Lanzhou 29
Brno 28
Belo Horizonte 27
Mexico City 27
Monmouth Junction 27
Kocaeli 26
Norwalk 25
Tashkent 25
Leawood 24
Nairobi 24
Mumbai 23
Poplar 23
Changchun 22
Totale 28.968
Nome #
Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation 388
CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid 387
Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window. 348
PEA and luteolin synergistically reduce mast cell-mediated toxicity and elicit neuroprotection in cell-based models of brain ischemia 346
Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling 346
1B/(-)IRE DMT1 Expression during Brain Ischemia Contributes to Cell Death Mediated by NF-κB/RelA Acetylation at Lys310 335
Glutamatergic neurons induce expression of functional glutamatergic synapses in primary myotubes. 334
Redistribution of DAT/α-synuclein complexes visualized by “in situ” proximity ligation assay in transgenic mice modelling early Parkinson’s disease 332
Priming of cultured neurons with sabeluzole results in long-lasting inhibition of neurotoxin-induced tau expression and cell death. 331
Glutamatergic Reinnervation and Assembly of Glutamatergic Synapses in Adult Rat Skeletal Muscle Occurs at Cholinergic Endplates 330
Glutamatergic reinnervation through peripheral nerve graft dictates assembly of glutamatergic synapses at rat skeletal muscle 328
NF-κB and epigenetic mechanisms as integrative regulators of brain resilience to anoxic stress. 317
GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity 305
NF-κB in Innate Neuroprotection and Age-Related Neurodegenerative Diseases 304
Late-onset Parkinsonism in NFκB/c-Rel-deficient mice. 295
Mild inflammatory profile without gliosis in the c-rel deficient mouse modeling a late-onset parkinsonism 279
Nicotine-induced structural plasticity in mesencephalic dopaminergic neurons is mediated by dopamine d3 receptors and akt-mtorc1 signaling 278
Synergistic association of valproate and resveratrol reduces brain injury in ischemic stroke 277
The End Is the Beginning: Parkinson's Disease in the Light of Brain Imaging 273
The Contribution of -Synuclein Spreading to Parkinson’s Disease Synaptopathy 272
The "in situ" proximity ligation assay to probe protein-protein interactions in intact tissues 244
NUOVO IMPIEGO TERAPEUTICO PREVENTIVO DELLA SUBUNITA' C-REL DELLA PROTEINA NF-KAPPAB E NUOVO IMPIEGO DI UN ANIMALE TRASGENICO NON UMANO CHE PORTA LA DELEZIONE DEL GENE C-REL (C-REL-/-) 232
Chapter 24 NF-KappaB Dimers in the Regulation of Neuronal Survival 223
NF-kappaB p50/RelA and c-Rel-containing dimers: opposite regulators of neuron vulnerability to ischaemia. 222
Role of Dopamine D2/D3 Receptors in Development, Plasticity, and Neuroprotection in Human iPSC-Derived Midbrain Dopaminergic Neurons 222
Mitochondria and alpha-synuclein: Friends or foes in the pathogenesis of Parkinson's disease? 220
The gamma-Secretase Modulator CHF5074 Reduces the Accumulation of Native Hyperphosphorylated Tau in a Transgenic Mouse Model of Alzheimer's Disease 219
An Integrated Approach for a Structural and Functional Evaluation of Biosimilars: Implications for Erythropoietin 219
The gamma-secretase modulator CHF5074 elicits neuroprotection and increases histone acetylation in primary cortical neurons exposed to oxygen glucose deprivation 217
Post-ischemic brain damage: NF-kappaB dimer heterogeneity as a molecular determinant of neuron vulnerability 213
Bim and Noxa are candidates to mediate the deleterious effect of the NF-kappa B subunit RelA in cerebral ischemia. 213
Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains 213
c-Rel deficient mice, a mouse model of "spreading" PD-like pathology. 209
A new pharmacological approach to the facilitation of acetylcholine transmission. 202
Targeting IKK2 by pharmacological inhibitor AS602868 prevents excitotoxic injury to neurons and oligodendrocytes. 202
Identification and characterization of a kappa B/Rel binding site in the regulatory region of the amyloid precursor protein gene. 201
Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2/D3 receptor activation 201
Spinal cord mGlu1a receptors - Possible target for amyotrophic lateral sclerosis therapy 199
Expression of functional NR1/NR2B-type NMDA receptors in neuronally differentiated SK-N-SH human cell line 195
Should we be cautious on the use of commercially available antibodies to dopamine receptors? 195
The proximity ligation assay: an high throughput technique for protein analysis in neuroscience 194
Inhibition of Survivin Is Associated with Zoledronic Acid-induced Apoptosis of Prostate Cancer Cells 193
Lack of coupling of D2 receptors to adenylate cyclase in GH3 cells exposed to epidermal growth factor. Possible role of a differential expression of Gi protein subtypes 191
Age-related changes of enkephalin in rat spinal cord 191
Structural plasticity in mesencephalic dopaminergic neurons produced by drugs of abuse: critical role of BDNF and dopamine 189
Different muscarinic receptor subtypes modulate proliferation of primary human detrusor smooth muscle cells via Akt/PI3K and map kinases. 187
From α-synuclein to synaptic dysfunctions: new insights into the pathophysiology of Parkinson's disease 186
α-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons 186
Synergistic association of valproate and resveratrol reduces brain injury in ischemic stroke. 183
Opposing roles for D-1 and D-2 dopamine receptors in the regulation of lower esophageal sphincter motility in the rat. 182
Depletion of Progranulin Reduces GluN2B-Containing NMDA Receptor Density, Tau Phosphorylation, and Dendritic Arborization in Mouse Primary Cortical Neurons 181
EXACERBATED AGE-DEPENDENT LOSS OF NIGRAL DOPAMINERGIC NEURONS IN NF-KAPPAB C-REL -/- MICE 181
Age-dependent changes in the mechanisms regulating dopamine uptake in the CNS 180
Acute scopolamine treatment decreases dopamine metabolism in rat hippocampus and frontal cortex 179
c-Rel deficient mice, a mouse model of “spreading” PD-like pathology 178
Alpha1 adrenoceptor subtypes in human urinary bladder: sex and regional comparison. 177
Involvement of Synapsin III in the onset of Alpha-synuclein pathology in Parkinson’s Disease 177
Nerve growth factor suppresses the transforming phenotype of human prolactinomas 176
Targeting of Disordered Proteins by Small Molecules in Neurodegenerative Diseases 176
Nerve growth factor and retinoic acid interactions in the control of small cell lung cancer proliferation. 175
Mitochondrial Dysfunction and Alpha-Synuclein Synaptic Pathology in Parkinson’s Disease: Who’s on First? 175
Synapsin III alterations in Parkinson's disease 174
Activation of NF-kappaB p65/c-Rel dimer is associated with neuroprotection elicited by mGlu5 receptor agonists against MPP(+) toxicity in SK-N-SH cells. 174
NF-κB unbalance and dysfunction in acute and age-related neurodegenerative disease 173
Nerve growth factor in the anterior pituitary: localization in mammotroph cells and co-secretion with prolactin by a dopamine-regulated mechanism 172
ALPHA-SYNUCLEIN MODULATES SYNAPSIN III IN NIGROSTRIATAL DOPAMINERGIC NEURONS: IMPLICATIONS FOR PARKINSON'S DISEASE 171
AAV-mediated overexpression of alpha-synuclein in midbrain dopamine neurons of Synapsin III knockout mice reveals novel molecular features involved in Parkinson's disease pathology. 171
Synapsin III and Alpha-Synuclein cooperation in the onset of synaptic pathology in Parkinson’s Disease 171
Clozapine-induced alteration of glucose homeostasis in the rat: the contribution of hypothalamic-pituitary-adrenal axis activation 169
Acetylation of NF-kappaB p50/RelA and histones in the epigenetic regulation of pro-apoptotic transcription: a neuroprotective target in brain ischemia 169
Degenerazione età –dipendente dei neuroni dopaminergici della sostanza nera nei topi NF-kappaB cRel 167
Cellular mechanisms for neurotensin receptor-mediated release of prolactin. 167
mGluR5 metabotropic glutamate receptor distribution in rat and human spinal cord: a developmental study. 165
Ketamine enhances structural plasticity in mouse mesencephalic and human iPSC-derived dopaminergic neurons via AMPAR-driven BDNF and mTOR signaling 165
Induction of tumour-suppressor phosphoprotein p53 in the apoptosis of cultured rat cerebellar neurones triggered by excitatory amino acids. 164
Nerve growth factor directs differentiation of the bipotential cell line GH-3 into the mammotroph phenotype 164
Epidermal growth factor induces the functional expression of dopamine receptors in the GH3 cell line 163
Computational and functional analysis of biopharmaceutical drugs in zebrafish: Erythropoietin as a test model 163
DIVALENT METAL TRANSPORTER 1-DEPENDENT ISCHEMIC NEURODEGENERATION: STRATEGIES TO KNOCKDOWN FERROUS IRON UPTAKE 162
The miR-21/PTEN/Akt signaling pathway is involved in the anti-tumoral effects of zoledronic acid in human breast cancer cell lines 160
SYNERGIC ROLE OF RESVERATROL AND HDACi MS-275 IN NEUROPROTECTION 159
Involvement of Synapsin III in the onset of alpha-synuclein synaptic pathology in Parkinson’s disease 158
Inhibition of IκBα phosphorylation prevents glutamate-induced NF-κB activation and neuronal cell death 158
The NMDA/D1 receptor complex as a new target in drug development 157
Identification of novel alternatively-spliced mRNA isoforms of metabotropic glutamate receptor 6 gene in rat and human retina. 156
A soluble interleukin-6 (IL6) recepetor/IL6 fusion protein enhances the in vitro differentiation of purified rat oligodendroglial lineage cells 156
Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of Parkinson’s disease and dementia with Lewy bodies, 156
Tau protein immunolocalization in fetal and adult human spinal cord. 155
Soluble interleukin-6 (IL-6) receptor/IL-6 fusion protein enhances in vitro differentiation of purified rat oligodendroglial lineage cells. 155
Chronic lead exposure differentially affects dopamine transport in rat striatum and nucleus accumbens. 155
Dimerization of dopamine D1 and D3 receptors in the regulation of striatal function 154
SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease. 154
Chronic lead exposure alters dopaminergic mechanisms in rat pituitary 154
Opposing regulation of tau protein levels by ionotropic and metabotropic glutamate receptors in human NT2 neurons 153
Acute hemodynamic and neurohumoral effects of the oral dopamine derivative ibopamine in patients with heart failure. 153
Angiotensin II differentially affects cyclic AMP formation in intact adrenal glomerulosa cells and in purified membrane preparations 153
A direct interaction between dopamine D1 receptor and phosphatase Shp-2 triggers Erk activation in striatal neurons 153
Metabotropic glutamate receptor mRNA expression in rat spinal cord 152
Synapsin III Alteration in Parkinson's disease 152
An in vitro method of diagnosing Parkinson's disease 151
Totale 20.781
Categoria #
all - tutte 196.225
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 196.225


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.557 0 0 0 0 26 71 138 137 116 310 208 551
2022/20232.035 333 35 68 175 180 584 0 192 294 26 70 78
2023/20241.962 127 36 159 126 108 461 72 84 400 31 40 318
2024/20254.772 29 57 36 612 530 335 492 122 650 309 981 619
2025/20268.974 862 1.213 647 1.353 871 586 1.364 344 561 722 328 123
2026/20273.722 494 458 948 1.356 466 0 0 0 0 0 0 0
Totale 43.993