SPANO, Pier Franco
 Distribuzione geografica
Continente #
NA - Nord America 18.854
EU - Europa 10.582
AS - Asia 9.497
SA - Sud America 1.640
Continente sconosciuto - Info sul continente non disponibili 931
AF - Africa 207
OC - Oceania 33
Totale 41.744
Nazione #
US - Stati Uniti d'America 18.529
CN - Cina 3.505
PL - Polonia 3.241
SG - Singapore 3.037
UA - Ucraina 2.073
BR - Brasile 1.361
DE - Germania 1.158
IT - Italia 1.033
HK - Hong Kong 934
FR - Francia 771
FI - Finlandia 650
VN - Vietnam 591
GB - Regno Unito 572
IN - India 473
RU - Federazione Russa 355
TR - Turchia 326
IE - Irlanda 324
BD - Bangladesh 183
CA - Canada 178
SE - Svezia 92
AR - Argentina 80
BE - Belgio 72
MX - Messico 69
ID - Indonesia 65
ZA - Sudafrica 64
IQ - Iraq 57
EC - Ecuador 49
NL - Olanda 49
CZ - Repubblica Ceca 41
JP - Giappone 37
KR - Corea 37
PK - Pakistan 37
ES - Italia 35
IR - Iran 35
VE - Venezuela 33
CO - Colombia 32
KE - Kenya 28
AU - Australia 27
UZ - Uzbekistan 27
CL - Cile 26
CH - Svizzera 23
EU - Europa 21
PY - Paraguay 21
MA - Marocco 20
NG - Nigeria 20
AT - Austria 19
IL - Israele 18
MU - Mauritius 18
EG - Egitto 17
SA - Arabia Saudita 16
UY - Uruguay 15
JM - Giamaica 12
JO - Giordania 12
PE - Perù 12
TN - Tunisia 12
ET - Etiopia 11
KZ - Kazakistan 10
TT - Trinidad e Tobago 10
BG - Bulgaria 9
BO - Bolivia 9
CR - Costa Rica 9
NP - Nepal 9
OM - Oman 9
SK - Slovacchia (Repubblica Slovacca) 9
AZ - Azerbaigian 8
GT - Guatemala 8
HN - Honduras 8
MY - Malesia 8
PH - Filippine 8
RO - Romania 8
DZ - Algeria 7
PS - Palestinian Territory 7
AE - Emirati Arabi Uniti 6
DO - Repubblica Dominicana 6
SV - El Salvador 6
AL - Albania 5
BA - Bosnia-Erzegovina 5
BH - Bahrain 5
LT - Lituania 5
PA - Panama 5
PT - Portogallo 5
TW - Taiwan 5
AM - Armenia 4
EE - Estonia 4
LV - Lettonia 4
NZ - Nuova Zelanda 4
RS - Serbia 4
TH - Thailandia 4
GE - Georgia 3
HR - Croazia 3
LK - Sri Lanka 3
MD - Moldavia 3
NI - Nicaragua 3
TJ - Tagikistan 3
BB - Barbados 2
BZ - Belize 2
CY - Cipro 2
DK - Danimarca 2
DM - Dominica 2
GD - Grenada 2
Totale 40.796
Città #
Warsaw 3.235
Fairfield 1.716
Woodbridge 1.712
Singapore 1.559
Jacksonville 1.484
Ashburn 1.466
Houston 1.022
Hong Kong 932
Ann Arbor 831
San Jose 821
Cambridge 721
Chandler 719
Seattle 666
Wilmington 657
Beijing 620
Princeton 589
Nanjing 573
The Dalles 499
Dearborn 406
Council Bluffs 372
New York 352
Helsinki 336
Dublin 323
Brescia 315
Los Angeles 290
Columbus 276
Istanbul 265
Lauterbourg 263
Nanchang 206
Des Moines 164
Shenyang 162
Ho Chi Minh City 161
Munich 145
Pune 141
Tianjin 140
Buffalo 135
Milan 133
Hebei 126
Changsha 125
Jinan 121
São Paulo 117
Moscow 107
Dallas 105
Santa Clara 102
Dong Ket 100
San Francisco 100
Lancaster 99
Hanoi 95
Chicago 91
Shanghai 88
San Diego 86
Jiaxing 80
Redondo Beach 79
London 77
Kunming 72
Brussels 68
Orem 68
Phoenix 58
Toronto 54
Hangzhou 53
Verona 53
Montreal 50
Turku 47
Ningbo 46
Rio de Janeiro 45
Rome 45
Brooklyn 44
Zhengzhou 42
Frankfurt am Main 40
Guangzhou 40
Taizhou 38
Denver 37
Boardman 35
Augusta 34
Chennai 34
Johannesburg 34
Manchester 34
Jakarta 33
Tokyo 33
San Mateo 31
Haikou 30
Ardabil 29
Lanzhou 29
Brasília 28
Brno 28
Atlanta 27
Boston 27
Mexico City 27
Monmouth Junction 27
Belo Horizonte 26
Kocaeli 26
Norwalk 25
Tashkent 25
Leawood 24
Nairobi 24
Mumbai 23
Poplar 23
Changchun 22
Dhaka 22
Haiphong 22
Totale 27.787
Nome #
CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid 379
Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation 370
Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window. 335
Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling 334
PEA and luteolin synergistically reduce mast cell-mediated toxicity and elicit neuroprotection in cell-based models of brain ischemia 333
1B/(-)IRE DMT1 Expression during Brain Ischemia Contributes to Cell Death Mediated by NF-κB/RelA Acetylation at Lys310 326
Redistribution of DAT/α-synuclein complexes visualized by “in situ” proximity ligation assay in transgenic mice modelling early Parkinson’s disease 324
Glutamatergic Reinnervation and Assembly of Glutamatergic Synapses in Adult Rat Skeletal Muscle Occurs at Cholinergic Endplates 322
Glutamatergic neurons induce expression of functional glutamatergic synapses in primary myotubes. 322
Glutamatergic reinnervation through peripheral nerve graft dictates assembly of glutamatergic synapses at rat skeletal muscle 321
Priming of cultured neurons with sabeluzole results in long-lasting inhibition of neurotoxin-induced tau expression and cell death. 311
NF-κB and epigenetic mechanisms as integrative regulators of brain resilience to anoxic stress. 304
GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity 299
NF-κB in Innate Neuroprotection and Age-Related Neurodegenerative Diseases 292
Late-onset Parkinsonism in NFκB/c-Rel-deficient mice. 284
Mild inflammatory profile without gliosis in the c-rel deficient mouse modeling a late-onset parkinsonism 271
The End Is the Beginning: Parkinson's Disease in the Light of Brain Imaging 270
Nicotine-induced structural plasticity in mesencephalic dopaminergic neurons is mediated by dopamine d3 receptors and akt-mtorc1 signaling 270
Synergistic association of valproate and resveratrol reduces brain injury in ischemic stroke 268
The Contribution of -Synuclein Spreading to Parkinson’s Disease Synaptopathy 264
The "in situ" proximity ligation assay to probe protein-protein interactions in intact tissues 230
NUOVO IMPIEGO TERAPEUTICO PREVENTIVO DELLA SUBUNITA' C-REL DELLA PROTEINA NF-KAPPAB E NUOVO IMPIEGO DI UN ANIMALE TRASGENICO NON UMANO CHE PORTA LA DELEZIONE DEL GENE C-REL (C-REL-/-) 223
Mitochondria and alpha-synuclein: Friends or foes in the pathogenesis of Parkinson's disease? 215
The gamma-Secretase Modulator CHF5074 Reduces the Accumulation of Native Hyperphosphorylated Tau in a Transgenic Mouse Model of Alzheimer's Disease 212
The gamma-secretase modulator CHF5074 elicits neuroprotection and increases histone acetylation in primary cortical neurons exposed to oxygen glucose deprivation 211
Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains 209
NF-kappaB p50/RelA and c-Rel-containing dimers: opposite regulators of neuron vulnerability to ischaemia. 208
Bim and Noxa are candidates to mediate the deleterious effect of the NF-kappa B subunit RelA in cerebral ischemia. 208
Role of Dopamine D2/D3 Receptors in Development, Plasticity, and Neuroprotection in Human iPSC-Derived Midbrain Dopaminergic Neurons 208
Post-ischemic brain damage: NF-kappaB dimer heterogeneity as a molecular determinant of neuron vulnerability 207
An Integrated Approach for a Structural and Functional Evaluation of Biosimilars: Implications for Erythropoietin 206
Chapter 24 NF-KappaB Dimers in the Regulation of Neuronal Survival 206
c-Rel deficient mice, a mouse model of "spreading" PD-like pathology. 201
Spinal cord mGlu1a receptors - Possible target for amyotrophic lateral sclerosis therapy 195
Targeting IKK2 by pharmacological inhibitor AS602868 prevents excitotoxic injury to neurons and oligodendrocytes. 194
Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2/D3 receptor activation 194
A new pharmacological approach to the facilitation of acetylcholine transmission. 190
Should we be cautious on the use of commercially available antibodies to dopamine receptors? 189
Inhibition of Survivin Is Associated with Zoledronic Acid-induced Apoptosis of Prostate Cancer Cells 188
The proximity ligation assay: an high throughput technique for protein analysis in neuroscience 186
Age-related changes of enkephalin in rat spinal cord 185
Expression of functional NR1/NR2B-type NMDA receptors in neuronally differentiated SK-N-SH human cell line 184
Identification and characterization of a kappa B/Rel binding site in the regulatory region of the amyloid precursor protein gene. 183
Different muscarinic receptor subtypes modulate proliferation of primary human detrusor smooth muscle cells via Akt/PI3K and map kinases. 183
α-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons 180
Lack of coupling of D2 receptors to adenylate cyclase in GH3 cells exposed to epidermal growth factor. Possible role of a differential expression of Gi protein subtypes 179
From α-synuclein to synaptic dysfunctions: new insights into the pathophysiology of Parkinson's disease 177
EXACERBATED AGE-DEPENDENT LOSS OF NIGRAL DOPAMINERGIC NEURONS IN NF-KAPPAB C-REL -/- MICE 177
Opposing roles for D-1 and D-2 dopamine receptors in the regulation of lower esophageal sphincter motility in the rat. 176
Depletion of Progranulin Reduces GluN2B-Containing NMDA Receptor Density, Tau Phosphorylation, and Dendritic Arborization in Mouse Primary Cortical Neurons 175
Acute scopolamine treatment decreases dopamine metabolism in rat hippocampus and frontal cortex 172
c-Rel deficient mice, a mouse model of “spreading” PD-like pathology 172
Structural plasticity in mesencephalic dopaminergic neurons produced by drugs of abuse: critical role of BDNF and dopamine 171
Alpha1 adrenoceptor subtypes in human urinary bladder: sex and regional comparison. 169
Activation of NF-kappaB p65/c-Rel dimer is associated with neuroprotection elicited by mGlu5 receptor agonists against MPP(+) toxicity in SK-N-SH cells. 169
Nerve growth factor and retinoic acid interactions in the control of small cell lung cancer proliferation. 168
Synapsin III alterations in Parkinson's disease 168
Mitochondrial Dysfunction and Alpha-Synuclein Synaptic Pathology in Parkinson’s Disease: Who’s on First? 167
Nerve growth factor suppresses the transforming phenotype of human prolactinomas 166
ALPHA-SYNUCLEIN MODULATES SYNAPSIN III IN NIGROSTRIATAL DOPAMINERGIC NEURONS: IMPLICATIONS FOR PARKINSON'S DISEASE 166
Targeting of Disordered Proteins by Small Molecules in Neurodegenerative Diseases 166
Synergistic association of valproate and resveratrol reduces brain injury in ischemic stroke. 166
Cellular mechanisms for neurotensin receptor-mediated release of prolactin. 162
Degenerazione età –dipendente dei neuroni dopaminergici della sostanza nera nei topi NF-kappaB cRel 161
Acetylation of NF-kappaB p50/RelA and histones in the epigenetic regulation of pro-apoptotic transcription: a neuroprotective target in brain ischemia 160
mGluR5 metabotropic glutamate receptor distribution in rat and human spinal cord: a developmental study. 159
Computational and functional analysis of biopharmaceutical drugs in zebrafish: Erythropoietin as a test model 159
Induction of tumour-suppressor phosphoprotein p53 in the apoptosis of cultured rat cerebellar neurones triggered by excitatory amino acids. 158
Nerve growth factor in the anterior pituitary: localization in mammotroph cells and co-secretion with prolactin by a dopamine-regulated mechanism 158
Clozapine-induced alteration of glucose homeostasis in the rat: the contribution of hypothalamic-pituitary-adrenal axis activation 156
SYNERGIC ROLE OF RESVERATROL AND HDACi MS-275 IN NEUROPROTECTION 156
Involvement of Synapsin III in the onset of alpha-synuclein synaptic pathology in Parkinson’s disease 155
Ketamine enhances structural plasticity in mouse mesencephalic and human iPSC-derived dopaminergic neurons via AMPAR-driven BDNF and mTOR signaling 155
Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of Parkinson’s disease and dementia with Lewy bodies, 154
Epidermal growth factor induces the functional expression of dopamine receptors in the GH3 cell line 153
Nerve growth factor directs differentiation of the bipotential cell line GH-3 into the mammotroph phenotype 152
Identification of novel alternatively-spliced mRNA isoforms of metabotropic glutamate receptor 6 gene in rat and human retina. 150
The miR-21/PTEN/Akt signaling pathway is involved in the anti-tumoral effects of zoledronic acid in human breast cancer cell lines 150
An in vitro method of diagnosing Parkinson's disease 149
Soluble interleukin-6 (IL-6) receptor/IL-6 fusion protein enhances in vitro differentiation of purified rat oligodendroglial lineage cells. 148
Synapsin III Alteration in Parkinson's disease 148
Tau protein immunolocalization in fetal and adult human spinal cord. 147
A direct interaction between dopamine D1 receptor and phosphatase Shp-2 triggers Erk activation in striatal neurons 147
AAV-mediated overexpression of alpha-synuclein in midbrain dopamine neurons of Synapsin III knockout mice reveals novel molecular features involved in Parkinson's disease pathology. 147
Dimerization of dopamine D1 and D3 receptors in the regulation of striatal function 146
A soluble interleukin-6 (IL6) recepetor/IL6 fusion protein enhances the in vitro differentiation of purified rat oligodendroglial lineage cells 146
Inhibition of IκBα phosphorylation prevents glutamate-induced NF-κB activation and neuronal cell death 146
Involvement of Synapsin III in the onset of Alpha-synuclein pathology in Parkinson’s Disease 146
Differential effects of caffeine on dihydroxyphenylacetic acid concentrations in various rat brain dopaminergic structures 145
PGRN gene silencing in primary neuronal cultures: a model of FTLD-U 145
Metabotropic glutamate receptor mRNA expression in rat spinal cord 144
The NMDA/D1 receptor complex as a new target in drug development 143
Synapsin III Alteration in Parkinson's disease 143
Acute hemodynamic and neurohumoral effects of the oral dopamine derivative ibopamine in patients with heart failure. 142
Gene expression profile activated by the chemokine CCL5/RANTES in human neuronal cells 142
SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease. 142
Chronic lead exposure differentially affects dopamine transport in rat striatum and nucleus accumbens. 142
Opposing regulation of tau protein levels by ionotropic and metabotropic glutamate receptors in human NT2 neurons 141
Chronic lead exposure alters dopaminergic mechanisms in rat pituitary 141
DIVALENT METAL TRANSPORTER 1-DEPENDENT ISCHEMIC NEURODEGENERATION: STRATEGIES TO KNOCKDOWN FERROUS IRON UPTAKE 141
Totale 19.777
Categoria #
all - tutte 188.819
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 188.819


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.681 0 0 34 90 26 71 138 137 116 310 208 551
2022/20232.035 333 35 68 175 180 584 0 192 294 26 70 78
2023/20241.962 127 36 159 126 108 461 72 84 400 31 40 318
2024/20254.772 29 57 36 612 530 335 492 122 650 309 981 619
2025/20268.974 862 1.213 647 1.353 871 586 1.364 344 561 722 328 123
2026/20271.473 494 458 521 0 0 0 0 0 0 0 0 0
Totale 41.744