SPANO, Pier Franco
 Distribuzione geografica
Continente #
NA - Nord America 12380
EU - Europa 8466
AS - Asia 2649
OC - Oceania 24
AF - Africa 21
Continente sconosciuto - Info sul continente non disponibili 21
SA - Sud America 20
Totale 23581
Nazione #
US - Stati Uniti d'America 12316
PL - Polonia 3198
CN - Cina 2252
UA - Ucraina 2030
DE - Germania 868
IT - Italia 684
FR - Francia 469
GB - Regno Unito 356
IE - Irlanda 312
FI - Finlandia 287
IN - India 190
VN - Vietnam 100
BE - Belgio 88
SE - Svezia 73
CA - Canada 63
RU - Federazione Russa 46
TR - Turchia 41
IR - Iran 31
AU - Australia 21
EU - Europa 21
MU - Mauritius 18
CH - Svizzera 16
KR - Corea 16
NL - Olanda 15
CL - Cile 8
BR - Brasile 7
ES - Italia 5
RO - Romania 5
IL - Israele 4
JP - Giappone 4
NZ - Nuova Zelanda 3
AR - Argentina 2
BA - Bosnia-Erzegovina 2
BD - Bangladesh 2
BG - Bulgaria 2
BO - Bolivia 2
EE - Estonia 2
ET - Etiopia 2
HK - Hong Kong 2
MK - Macedonia 2
SK - Slovacchia (Repubblica Slovacca) 2
TH - Thailandia 2
AM - Armenia 1
GE - Georgia 1
GR - Grecia 1
HU - Ungheria 1
LU - Lussemburgo 1
MX - Messico 1
OM - Oman 1
PE - Perù 1
PK - Pakistan 1
SA - Arabia Saudita 1
SI - Slovenia 1
SL - Sierra Leone 1
Totale 23581
Città #
Warsaw 3198
Fairfield 1716
Woodbridge 1712
Jacksonville 1480
Houston 1002
Ann Arbor 831
Cambridge 721
Chandler 719
Ashburn 673
Wilmington 655
Seattle 640
Princeton 588
Nanjing 572
Dearborn 406
Dublin 311
Beijing 296
Brescia 291
Nanchang 204
Shenyang 160
Des Moines 143
Tianjin 131
Hebei 126
Changsha 119
Jinan 116
Dong Ket 100
Lancaster 97
Brussels 86
San Diego 84
Jiaxing 79
Milan 78
Kunming 69
Verona 47
Hangzhou 46
Ningbo 44
Taizhou 38
Toronto 38
London 37
Zhengzhou 34
San Francisco 33
San Mateo 31
Haikou 30
Ardabil 29
Augusta 29
Lanzhou 28
Monmouth Junction 27
Kocaeli 26
Guangzhou 25
Leawood 24
Helsinki 22
Boardman 20
Orange 20
Changchun 19
Norwalk 18
Fuzhou 17
Basel 16
Shanghai 15
Hefei 14
Ottawa 14
Phoenix 14
Rome 14
San Donà Di Piave 14
Taiyuan 11
Canberra 9
New York 8
Nürnberg 8
Teramo 8
Auburn Hills 7
Redwood City 7
Seoul 6
Vicenza 6
Bologna 5
Chicago 5
Hanover 5
Melbourne 5
Mumbai 5
Redmond 5
Dallas 4
Fulda 4
Madrid 4
Oxford 4
Sydney 4
Torino 4
Walnut 4
Corridonia 3
Cremona 3
Detroit 3
Falls Church 3
Fremont 3
Indiana 3
Markham 3
Moscow 3
Paris 3
Sondrio 3
São Paulo 3
Almere Stad 2
Amsterdam 2
Auckland 2
Bangalore 2
Bangkok 2
Berlin 2
Totale 18359
Nome #
CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid 291
Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation 258
PEA and luteolin synergistically reduce mast cell-mediated toxicity and elicit neuroprotection in cell-based models of brain ischemia 253
Glutamatergic neurons induce expression of functional glutamatergic synapses in primary myotubes. 244
Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling 240
Redistribution of DAT/α-synuclein complexes visualized by “in situ” proximity ligation assay in transgenic mice modelling early Parkinson’s disease 238
Glutamatergic Reinnervation and Assembly of Glutamatergic Synapses in Adult Rat Skeletal Muscle Occurs at Cholinergic Endplates 235
Glutamatergic reinnervation through peripheral nerve graft dictates assembly of glutamatergic synapses at rat skeletal muscle 234
1B/(-)IRE DMT1 Expression during Brain Ischemia Contributes to Cell Death Mediated by NF-κB/RelA Acetylation at Lys310 220
GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity 220
The End Is the Beginning: Parkinson's Disease in the Light of Brain Imaging 220
NF-κB in Innate Neuroprotection and Age-Related Neurodegenerative Diseases 216
NF-κB and epigenetic mechanisms as integrative regulators of brain resilience to anoxic stress. 213
The Contribution of -Synuclein Spreading to Parkinson’s Disease Synaptopathy 212
Late-onset Parkinsonism in NFκB/c-Rel-deficient mice. 208
Mild inflammatory profile without gliosis in the c-rel deficient mouse modeling a late-onset parkinsonism 208
Synergistic association of valproate and resveratrol reduces brain injury in ischemic stroke 208
Nicotine-induced structural plasticity in mesencephalic dopaminergic neurons is mediated by dopamine d3 receptors and akt-mtorc1 signaling 206
Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window. 200
Priming of cultured neurons with sabeluzole results in long-lasting inhibition of neurotoxin-induced tau expression and cell death. 199
Mitochondria and alpha-synuclein: Friends or foes in the pathogenesis of Parkinson's disease? 155
NUOVO IMPIEGO TERAPEUTICO PREVENTIVO DELLA SUBUNITA' C-REL DELLA PROTEINA NF-KAPPAB E NUOVO IMPIEGO DI UN ANIMALE TRASGENICO NON UMANO CHE PORTA LA DELEZIONE DEL GENE C-REL (C-REL-/-) 152
The "in situ" proximity ligation assay to probe protein-protein interactions in intact tissues 150
Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains 145
The gamma-Secretase Modulator CHF5074 Reduces the Accumulation of Native Hyperphosphorylated Tau in a Transgenic Mouse Model of Alzheimer's Disease 144
Spinal cord mGlu1a receptors - Possible target for amyotrophic lateral sclerosis therapy 142
Targeting IKK2 by pharmacological inhibitor AS602868 prevents excitotoxic injury to neurons and oligodendrocytes. 138
Role of Dopamine D2/D3 Receptors in Development, Plasticity, and Neuroprotection in Human iPSC-Derived Midbrain Dopaminergic Neurons 138
Post-ischemic brain damage: NF-kappaB dimer heterogeneity as a molecular determinant of neuron vulnerability 136
NF-kappaB p50/RelA and c-Rel-containing dimers: opposite regulators of neuron vulnerability to ischaemia. 136
Bim and Noxa are candidates to mediate the deleterious effect of the NF-kappa B subunit RelA in cerebral ischemia. 135
Targeting of Disordered Proteins by Small Molecules in Neurodegenerative Diseases 131
Different muscarinic receptor subtypes modulate proliferation of primary human detrusor smooth muscle cells via Akt/PI3K and map kinases. 126
Chapter 24 NF-KappaB Dimers in the Regulation of Neuronal Survival 122
Structural plasticity in mesencephalic dopaminergic neurons produced by drugs of abuse: critical role of BDNF and dopamine 120
Identification and characterization of a kappa B/Rel binding site in the regulatory region of the amyloid precursor protein gene. 116
Inhibition of Survivin Is Associated with Zoledronic Acid-induced Apoptosis of Prostate Cancer Cells 116
An Integrated Approach for a Structural and Functional Evaluation of Biosimilars: Implications for Erythropoietin 115
Age-related changes of enkephalin in rat spinal cord 113
Cellular mechanisms for neurotensin receptor-mediated release of prolactin. 113
Expression of functional NR1/NR2B-type NMDA receptors in neuronally differentiated SK-N-SH human cell line 111
mGluR5 metabotropic glutamate receptor distribution in rat and human spinal cord: a developmental study. 107
A new pharmacological approach to the facilitation of acetylcholine transmission. 106
Differential effects of caffeine on dihydroxyphenylacetic acid concentrations in various rat brain dopaminergic structures 105
The proximity ligation assay: an high throughput technique for protein analysis in neuroscience 105
Dopamine receptors are present in rat and human esophagus 103
The tyrosine phosphatase Shp-2 interacts with the dopamine D(1) receptor and triggers D(1) -mediated Erk signaling in striatal neurons. 103
Differential gene expression of cholinergic muscarinic receptor subtypes in male and female normal human urinary bladder. 103
Induction of tumour-suppressor phosphoprotein p53 in the apoptosis of cultured rat cerebellar neurones triggered by excitatory amino acids. 102
Nerve growth factor suppresses the transforming phenotype of human prolactinomas 102
Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2/D3 receptor activation 102
From α-synuclein to synaptic dysfunctions: new insights into the pathophysiology of Parkinson's disease 102
Metabotropic glutamate receptor mRNA expression in rat spinal cord 102
SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease. 101
The gamma-secretase modulator CHF5074 elicits neuroprotection and increases histone acetylation in primary cortical neurons exposed to oxygen glucose deprivation 101
Vasoactive Intestinal Polypeptide (VIP) selectively stimulates prolactin release in healthy women 101
Opposing regulation of tau protein levels by ionotropic and metabotropic glutamate receptors in human NT2 neurons 100
The neurobiology of dopamine receptors: evolution from the dual concept to heterodimer complexes 100
Tau protein immunolocalization in fetal and adult human spinal cord. 99
Clozapine-induced alteration of glucose homeostasis in the rat: the contribution of hypothalamic-pituitary-adrenal axis activation 99
Synergistic association of valproate and resveratrol reduces brain injury in ischemic stroke. 99
c-Rel deficient mice, a mouse model of "spreading" PD-like pathology. 99
Sex-related variations in serum nerve growth factor concentration in humans. 98
Identification of D2 dopaminergic receptors in bovine adrenal cortex. 98
Chronic lead exposure alters dopaminergic mechanisms in rat pituitary 97
Effect of lead exposure on dopaminergic receptors in rat striatum and nucleus accumbens 97
Nerve growth factor directs differentiation of the bipotential cell line GH-3 into the mammotroph phenotype 96
SYNERGIC ROLE OF RESVERATROL AND HDACi MS-275 IN NEUROPROTECTION 96
Post-synaptic D1 and D2 dopamine receptors are present in rabbit renal and mesenteric arteries 96
Mitochondrial Dysfunction and Alpha-Synuclein Synaptic Pathology in Parkinson’s Disease: Who’s on First? 96
Identification of novel alternatively-spliced mRNA isoforms of metabotropic glutamate receptor 6 gene in rat and human retina. 95
Synapsin III alterations in Parkinson's disease 95
Acute scopolamine treatment decreases dopamine metabolism in rat hippocampus and frontal cortex 94
Prevention of neuron and oligodendrocyte degeneration by interleukin-6 (IL-6) and IL-6 receptor/IL-6 fusion protein in organotypic hippocampal slices 94
Chronic lead exposure differentially affects dopamine transport in rat striatum and nucleus accumbens. 94
Evidence for the presence of D1 and D2 dopamine receptors in the rat adrenal cortex 94
Computational and functional analysis of biopharmaceutical drugs in zebrafish: Erythropoietin as a test model 94
Different neurotransmitter systems are involved in the development of esophageal achalasia 93
Evidence for the presence of both D-1 and D-2 dopamine receptors in human esophagus. 93
Opposing roles for D-1 and D-2 dopamine receptors in the regulation of lower esophageal sphincter motility in the rat. 93
Selective disarrangement of the rostral telencephalic cholinergic system in heterozygous reeler mice. 93
Clinical Outcome After Extended Endovascular Recanalization in Buerger's Disease in 20 Consecutive Cases. 93
Alpha1 adrenoceptor subtypes in human urinary bladder: sex and regional comparison. 92
The NMDA/D1 receptor complex as a new target in drug development 92
The miR-21/PTEN/Akt signaling pathway is involved in the anti-tumoral effects of zoledronic acid in human breast cancer cell lines 92
EXACERBATED AGE-DEPENDENT LOSS OF NIGRAL DOPAMINERGIC NEURONS IN NF-KAPPAB C-REL -/- MICE 92
Nerve growth factor in pituitary development and pituitary tumors 91
α-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons 91
Depletion of Progranulin Reduces GluN2B-Containing NMDA Receptor Density, Tau Phosphorylation, and Dendritic Arborization in Mouse Primary Cortical Neurons 91
Epidermal growth factor induces the functional expression of dopamine receptors in the GH3 cell line 90
Inhibition of aldosterone secretion by dopamine, ibopamine, and dihydroergotoxine in patients with congestive heart failure 90
Neuroprotection by metabotropic glutamate receptor agonists on kainate-induced degeneration of motor neurons in spinal cord slices from adult rat. 90
Pharmacological characterization of D1 and D2 dopamine receptors in rat limbocortical areas. II. Dorsal hippocampus 89
Gene expression profile activated by the chemokine CCL5/RANTES in human neuronal cells 89
The inhibitor of IkappaBalpha phosphorylation BAY 11-7082 prevents NMDA neurotoxicity in mouse hippocampal slices. 89
Role of receptor heterodimers in the development of L-dopa-induced dyskinesias in the 6-hydroxydopamine rat model of Parkinson's disease. 89
Glycogen synthase kinase-3 inhibition reducesischemic cerebral damage, restores impaired mitochondrial biogenesis and preventsROS production 89
Angiotensin II differentially affects cyclic AMP formation in intact adrenal glomerulosa cells and in purified membrane preparations 88
Nerve growth factor in the anterior pituitary: localization in mammotroph cells and co-secretion with prolactin by a dopamine-regulated mechanism 88
c-Rel deficient mice, a mouse model of “spreading” PD-like pathology 88
Totale 12937
Categoria #
all - tutte 59857
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 59857


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2017/2018354 0000 00 00 00238116
2018/20193255 5713012986 360145 362376 122356594538
2019/20207822 1108274295755 431971 780870 4871102303446
2020/20214303 108520106542 150489 170532 681321506178
2021/20222375 1695253490 2671 138137 116310208551
2022/20231959 3333568175 180584 5198 30332460
Totale 24487