SPANO, Pier Franco
 Distribuzione geografica
Continente #
NA - Nord America 15.577
EU - Europa 9.847
AS - Asia 8.318
SA - Sud America 1.493
AF - Africa 145
OC - Oceania 31
Continente sconosciuto - Info sul continente non disponibili 22
Totale 35.433
Nazione #
US - Stati Uniti d'America 15.363
PL - Polonia 3.234
CN - Cina 3.198
SG - Singapore 2.598
UA - Ucraina 2.067
BR - Brasile 1.295
DE - Germania 1.125
HK - Hong Kong 899
IT - Italia 854
FI - Finlandia 543
GB - Regno Unito 527
FR - Francia 484
VN - Vietnam 468
IN - India 416
RU - Federazione Russa 347
TR - Turchia 324
IE - Irlanda 320
CA - Canada 122
BD - Bangladesh 88
SE - Svezia 87
BE - Belgio 66
AR - Argentina 63
MX - Messico 55
ZA - Sudafrica 52
ID - Indonesia 50
CZ - Repubblica Ceca 41
EC - Ecuador 38
IQ - Iraq 37
NL - Olanda 36
IR - Iran 35
KR - Corea 35
AU - Australia 25
ES - Italia 24
KE - Kenya 24
JP - Giappone 23
UZ - Uzbekistan 23
CH - Svizzera 21
EU - Europa 21
PK - Pakistan 19
PY - Paraguay 19
MU - Mauritius 18
AT - Austria 17
CO - Colombia 17
IL - Israele 17
MA - Marocco 16
VE - Venezuela 16
CL - Cile 13
EG - Egitto 13
UY - Uruguay 13
SA - Arabia Saudita 12
PE - Perù 10
JO - Giordania 9
KZ - Kazakistan 9
AZ - Azerbaigian 8
ET - Etiopia 8
OM - Oman 8
TT - Trinidad e Tobago 8
BG - Bulgaria 7
BO - Bolivia 7
SK - Slovacchia (Repubblica Slovacca) 7
JM - Giamaica 6
RO - Romania 6
AE - Emirati Arabi Uniti 5
PS - Palestinian Territory 5
TN - Tunisia 5
DZ - Algeria 4
EE - Estonia 4
GT - Guatemala 4
HN - Honduras 4
LT - Lituania 4
NP - Nepal 4
NZ - Nuova Zelanda 4
PA - Panama 4
PT - Portogallo 4
AL - Albania 3
AM - Armenia 3
DO - Repubblica Dominicana 3
LV - Lettonia 3
RS - Serbia 3
TW - Taiwan 3
BA - Bosnia-Erzegovina 2
BH - Bahrain 2
CR - Costa Rica 2
CY - Cipro 2
GD - Grenada 2
GE - Georgia 2
GR - Grecia 2
GY - Guiana 2
LK - Sri Lanka 2
MD - Moldavia 2
MK - Macedonia 2
TH - Thailandia 2
TJ - Tagikistan 2
TM - Turkmenistan 2
AO - Angola 1
BB - Barbados 1
BN - Brunei Darussalam 1
BW - Botswana 1
BZ - Belize 1
CG - Congo 1
Totale 35.414
Città #
Warsaw 3.230
Fairfield 1.716
Woodbridge 1.712
Jacksonville 1.484
Ashburn 1.181
Singapore 1.166
Houston 1.012
Hong Kong 897
Ann Arbor 831
Cambridge 721
Chandler 719
Seattle 659
Wilmington 657
Beijing 594
Princeton 588
Nanjing 572
Dearborn 406
Dublin 318
Brescia 311
New York 292
Istanbul 264
Los Angeles 254
Helsinki 229
Nanchang 206
Des Moines 162
Shenyang 162
Munich 145
Pune 141
Tianjin 140
Buffalo 128
Hebei 126
Changsha 125
Ho Chi Minh City 124
Jinan 121
The Dalles 110
Moscow 105
São Paulo 104
Dong Ket 100
Lancaster 98
Milan 94
San Diego 84
Shanghai 83
San Francisco 81
Jiaxing 80
Redondo Beach 79
Kunming 72
Hanoi 67
London 65
Brussels 64
Dallas 62
Chicago 59
Santa Clara 53
Toronto 51
Verona 50
Hangzhou 48
Turku 47
Ningbo 44
Rio de Janeiro 43
Zhengzhou 42
Guangzhou 38
Taizhou 38
Phoenix 33
Augusta 32
Brooklyn 32
San Mateo 31
Haikou 30
Jakarta 30
Ardabil 29
Boardman 29
Lanzhou 29
Brno 28
Brasília 27
Johannesburg 27
Monmouth Junction 27
Kocaeli 26
Belo Horizonte 25
Denver 25
Montreal 25
Norwalk 25
Leawood 24
Boston 23
Rome 23
Changchun 22
Manchester 22
Mexico City 22
Tashkent 22
Tokyo 21
Atlanta 20
Haiphong 20
Nairobi 20
Orange 20
Frankfurt am Main 19
Dhaka 18
Fuzhou 17
Poplar 17
Porto Alegre 17
Basel 16
Mumbai 16
Chennai 15
Orem 15
Totale 24.173
Nome #
CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid 355
Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation 335
PEA and luteolin synergistically reduce mast cell-mediated toxicity and elicit neuroprotection in cell-based models of brain ischemia 310
Glutamatergic neurons induce expression of functional glutamatergic synapses in primary myotubes. 309
Glutamatergic Reinnervation and Assembly of Glutamatergic Synapses in Adult Rat Skeletal Muscle Occurs at Cholinergic Endplates 299
Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling 298
Redistribution of DAT/α-synuclein complexes visualized by “in situ” proximity ligation assay in transgenic mice modelling early Parkinson’s disease 293
1B/(-)IRE DMT1 Expression during Brain Ischemia Contributes to Cell Death Mediated by NF-κB/RelA Acetylation at Lys310 292
GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity 279
Glutamatergic reinnervation through peripheral nerve graft dictates assembly of glutamatergic synapses at rat skeletal muscle 278
Priming of cultured neurons with sabeluzole results in long-lasting inhibition of neurotoxin-induced tau expression and cell death. 272
NF-κB and epigenetic mechanisms as integrative regulators of brain resilience to anoxic stress. 270
Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window. 268
NF-κB in Innate Neuroprotection and Age-Related Neurodegenerative Diseases 266
The End Is the Beginning: Parkinson's Disease in the Light of Brain Imaging 255
Late-onset Parkinsonism in NFκB/c-Rel-deficient mice. 253
Mild inflammatory profile without gliosis in the c-rel deficient mouse modeling a late-onset parkinsonism 251
The Contribution of -Synuclein Spreading to Parkinson’s Disease Synaptopathy 248
Synergistic association of valproate and resveratrol reduces brain injury in ischemic stroke 243
Nicotine-induced structural plasticity in mesencephalic dopaminergic neurons is mediated by dopamine d3 receptors and akt-mtorc1 signaling 234
The "in situ" proximity ligation assay to probe protein-protein interactions in intact tissues 210
Mitochondria and alpha-synuclein: Friends or foes in the pathogenesis of Parkinson's disease? 200
Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains 192
An Integrated Approach for a Structural and Functional Evaluation of Biosimilars: Implications for Erythropoietin 190
Role of Dopamine D2/D3 Receptors in Development, Plasticity, and Neuroprotection in Human iPSC-Derived Midbrain Dopaminergic Neurons 190
Chapter 24 NF-KappaB Dimers in the Regulation of Neuronal Survival 187
Targeting IKK2 by pharmacological inhibitor AS602868 prevents excitotoxic injury to neurons and oligodendrocytes. 184
The gamma-Secretase Modulator CHF5074 Reduces the Accumulation of Native Hyperphosphorylated Tau in a Transgenic Mouse Model of Alzheimer's Disease 184
NUOVO IMPIEGO TERAPEUTICO PREVENTIVO DELLA SUBUNITA' C-REL DELLA PROTEINA NF-KAPPAB E NUOVO IMPIEGO DI UN ANIMALE TRASGENICO NON UMANO CHE PORTA LA DELEZIONE DEL GENE C-REL (C-REL-/-) 184
c-Rel deficient mice, a mouse model of "spreading" PD-like pathology. 180
Spinal cord mGlu1a receptors - Possible target for amyotrophic lateral sclerosis therapy 179
Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2/D3 receptor activation 176
Inhibition of Survivin Is Associated with Zoledronic Acid-induced Apoptosis of Prostate Cancer Cells 176
Post-ischemic brain damage: NF-kappaB dimer heterogeneity as a molecular determinant of neuron vulnerability 173
NF-kappaB p50/RelA and c-Rel-containing dimers: opposite regulators of neuron vulnerability to ischaemia. 172
Different muscarinic receptor subtypes modulate proliferation of primary human detrusor smooth muscle cells via Akt/PI3K and map kinases. 171
Bim and Noxa are candidates to mediate the deleterious effect of the NF-kappa B subunit RelA in cerebral ischemia. 169
Identification and characterization of a kappa B/Rel binding site in the regulatory region of the amyloid precursor protein gene. 163
Age-related changes of enkephalin in rat spinal cord 163
The proximity ligation assay: an high throughput technique for protein analysis in neuroscience 163
Expression of functional NR1/NR2B-type NMDA receptors in neuronally differentiated SK-N-SH human cell line 160
A new pharmacological approach to the facilitation of acetylcholine transmission. 159
α-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons 158
Targeting of Disordered Proteins by Small Molecules in Neurodegenerative Diseases 158
From α-synuclein to synaptic dysfunctions: new insights into the pathophysiology of Parkinson's disease 155
Depletion of Progranulin Reduces GluN2B-Containing NMDA Receptor Density, Tau Phosphorylation, and Dendritic Arborization in Mouse Primary Cortical Neurons 154
EXACERBATED AGE-DEPENDENT LOSS OF NIGRAL DOPAMINERGIC NEURONS IN NF-KAPPAB C-REL -/- MICE 154
Cellular mechanisms for neurotensin receptor-mediated release of prolactin. 151
c-Rel deficient mice, a mouse model of “spreading” PD-like pathology 150
The gamma-secretase modulator CHF5074 elicits neuroprotection and increases histone acetylation in primary cortical neurons exposed to oxygen glucose deprivation 149
Activation of NF-kappaB p65/c-Rel dimer is associated with neuroprotection elicited by mGlu5 receptor agonists against MPP(+) toxicity in SK-N-SH cells. 149
Alpha1 adrenoceptor subtypes in human urinary bladder: sex and regional comparison. 148
Structural plasticity in mesencephalic dopaminergic neurons produced by drugs of abuse: critical role of BDNF and dopamine 148
Nerve growth factor suppresses the transforming phenotype of human prolactinomas 147
Synapsin III alterations in Parkinson's disease 147
Mitochondrial Dysfunction and Alpha-Synuclein Synaptic Pathology in Parkinson’s Disease: Who’s on First? 145
Acute scopolamine treatment decreases dopamine metabolism in rat hippocampus and frontal cortex 144
ALPHA-SYNUCLEIN MODULATES SYNAPSIN III IN NIGROSTRIATAL DOPAMINERGIC NEURONS: IMPLICATIONS FOR PARKINSON'S DISEASE 144
Computational and functional analysis of biopharmaceutical drugs in zebrafish: Erythropoietin as a test model 144
Synergistic association of valproate and resveratrol reduces brain injury in ischemic stroke. 143
Degenerazione età –dipendente dei neuroni dopaminergici della sostanza nera nei topi NF-kappaB cRel 142
SYNERGIC ROLE OF RESVERATROL AND HDACi MS-275 IN NEUROPROTECTION 141
mGluR5 metabotropic glutamate receptor distribution in rat and human spinal cord: a developmental study. 139
Induction of tumour-suppressor phosphoprotein p53 in the apoptosis of cultured rat cerebellar neurones triggered by excitatory amino acids. 139
Nerve growth factor in the anterior pituitary: localization in mammotroph cells and co-secretion with prolactin by a dopamine-regulated mechanism 139
Clozapine-induced alteration of glucose homeostasis in the rat: the contribution of hypothalamic-pituitary-adrenal axis activation 139
The miR-21/PTEN/Akt signaling pathway is involved in the anti-tumoral effects of zoledronic acid in human breast cancer cell lines 139
Identification of novel alternatively-spliced mRNA isoforms of metabotropic glutamate receptor 6 gene in rat and human retina. 137
Opposing roles for D-1 and D-2 dopamine receptors in the regulation of lower esophageal sphincter motility in the rat. 137
Soluble interleukin-6 (IL-6) receptor/IL-6 fusion protein enhances in vitro differentiation of purified rat oligodendroglial lineage cells. 136
Differential effects of caffeine on dihydroxyphenylacetic acid concentrations in various rat brain dopaminergic structures 136
Metabotropic glutamate receptor mRNA expression in rat spinal cord 136
Acetylation of NF-kappaB p50/RelA and histones in the epigenetic regulation of pro-apoptotic transcription: a neuroprotective target in brain ischemia 135
Involvement of Synapsin III in the onset of alpha-synuclein synaptic pathology in Parkinson’s disease 135
Ketamine enhances structural plasticity in mouse mesencephalic and human iPSC-derived dopaminergic neurons via AMPAR-driven BDNF and mTOR signaling 134
Tau protein immunolocalization in fetal and adult human spinal cord. 133
Dopamine receptors are present in rat and human esophagus 132
Nerve growth factor directs differentiation of the bipotential cell line GH-3 into the mammotroph phenotype 131
Inhibition of IκBα phosphorylation prevents glutamate-induced NF-κB activation and neuronal cell death 131
Differential gene expression of cholinergic muscarinic receptor subtypes in male and female normal human urinary bladder. 130
Opposing regulation of tau protein levels by ionotropic and metabotropic glutamate receptors in human NT2 neurons 129
Gene expression profile activated by the chemokine CCL5/RANTES in human neuronal cells 129
Epidermal growth factor induces the functional expression of dopamine receptors in the GH3 cell line 128
Nerve growth factor signaling in prostate health and disease. 128
Sex-related variations in serum nerve growth factor concentration in humans. 127
Chronic lead exposure alters dopaminergic mechanisms in rat pituitary 127
Dimerization of dopamine D1 and D3 receptors in the regulation of striatal function 126
Evidence for the presence of D1 and D2 dopamine receptors in the rat adrenal cortex 126
An in vitro method of diagnosing Parkinson's disease 126
The neurobiology of dopamine receptors: evolution from the dual concept to heterodimer complexes 125
Identification of D2 dopaminergic receptors in bovine adrenal cortex. 125
SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease. 124
The tyrosine phosphatase Shp-2 interacts with the dopamine D(1) receptor and triggers D(1) -mediated Erk signaling in striatal neurons. 124
Chronic lead exposure differentially affects dopamine transport in rat striatum and nucleus accumbens. 124
Different neurotransmitter systems are involved in the development of esophageal achalasia 123
The NMDA/D1 receptor complex as a new target in drug development 123
Detection of muscarinic receptor subtypes in human urinary bladder mucosa: Age and gender-dependent modifications 123
Vasoactive Intestinal Polypeptide (VIP) selectively stimulates prolactin release in healthy women 123
Effect of lead exposure on dopaminergic receptors in rat striatum and nucleus accumbens 123
Evidence for the presence of both D-1 and D-2 dopamine receptors in human esophagus. 121
Totale 17.446
Categoria #
all - tutte 162.033
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 162.033


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20212.877 0 0 0 0 0 489 170 532 681 321 506 178
2021/20222.375 169 525 34 90 26 71 138 137 116 310 208 551
2022/20232.035 333 35 68 175 180 584 0 192 294 26 70 78
2023/20241.962 127 36 159 126 108 461 72 84 400 31 40 318
2024/20254.772 29 57 36 612 530 335 492 122 650 309 981 619
2025/20265.044 862 1.213 647 1.353 871 98 0 0 0 0 0 0
Totale 36.341