Bignotti, Mattia
Bignotti, Mattia
Dipartimento di Medicina Molecolare e Traslazionale
Characterization of Novel Alpha-1-Antitrypsin Coding Variants in a Mammalian Cellular Model
2024-01-01 Denardo, Andrea; Ben Khlifa, Emna; Bignotti, Mattia; Fra, Annamaria
Computational prediction of (alpha-1antitrypsin)-elastase Michaelis complex reveals an exosite contributing to high-affinity interaction
2024-01-01 Gangemi, R; Bignotti, M; Denardo, A; Lomas, Da; Irving, Ja; Fra, A; Gangemi, F
Development of a novel assay to measure alpha-1-antitrypsin inhibitory activity toward neutrophil elastase
2024-01-01 Bignotti, M; Gambelli, J; Denardo, A; Miranda, E; Irving, Ja; Fra, A
Functional characterization of amino acid variants of the reactive-center-loop of alpha-1-antitrypsin
2022-01-01 BEN KHLIFA, Emna; Bignotti, Mattia; Bartoli, Giulia; Denardo, Andrea; Fra, Annamaria
Identification of an exosite at the neutrophil elastase/alpha‐1‐antitrypsin interface
2025-01-01 Gangemi, Roberto; Bignotti, Mattia; Denardo, Andrea; Pearce, Claudia N.; Ronzoni, Riccardo; Lomas, David A.; Irving, James A.; Fra, Annamaria; Gangemi, Fabrizio
Probing of the reactive center loop region of alpha-1-antitrypsin by mutagenesis predicts new type-2 dysfunctional variants
2024-01-01 Denardo, A.; Ben Khlifa, E.; Bignotti, M.; Giuliani, R.; D’Acunto, E.; Miranda, E.; Irving, J. A.; Fra, A.
Quantification of circulating alpha-1-antitrypsin polymers associated with different SERPINA1 genotypes
2024-01-01 Balderacchi, Alice M.; Bignotti, Mattia; Ottaviani, Stefania; Denardo, Andrea; Barzon, Valentina; Ben Khlifa, Emna; Vailati, Guido; Piloni, Davide; Benini, Federica; Corda, Luciano; Corsico, Angelo G.; Ferrarotti, Ilaria; Fra, Annamaria
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Characterization of Novel Alpha-1-Antitrypsin Coding Variants in a Mammalian Cellular Model | 1-gen-2024 | Denardo, Andrea; Ben Khlifa, Emna; Bignotti, Mattia; Fra, Annamaria | |
| Computational prediction of (alpha-1antitrypsin)-elastase Michaelis complex reveals an exosite contributing to high-affinity interaction | 1-gen-2024 | Gangemi, R; Bignotti, M; Denardo, A; Lomas, Da; Irving, Ja; Fra, A; Gangemi, F | |
| Development of a novel assay to measure alpha-1-antitrypsin inhibitory activity toward neutrophil elastase | 1-gen-2024 | Bignotti, M; Gambelli, J; Denardo, A; Miranda, E; Irving, Ja; Fra, A | |
| Functional characterization of amino acid variants of the reactive-center-loop of alpha-1-antitrypsin | 1-gen-2022 | BEN KHLIFA, Emna; Bignotti, Mattia; Bartoli, Giulia; Denardo, Andrea; Fra, Annamaria | |
| Identification of an exosite at the neutrophil elastase/alpha‐1‐antitrypsin interface | 1-gen-2025 | Gangemi, Roberto; Bignotti, Mattia; Denardo, Andrea; Pearce, Claudia N.; Ronzoni, Riccardo; Lomas, David A.; Irving, James A.; Fra, Annamaria; Gangemi, Fabrizio | |
| Probing of the reactive center loop region of alpha-1-antitrypsin by mutagenesis predicts new type-2 dysfunctional variants | 1-gen-2024 | Denardo, A.; Ben Khlifa, E.; Bignotti, M.; Giuliani, R.; D’Acunto, E.; Miranda, E.; Irving, J. A.; Fra, A. | |
| Quantification of circulating alpha-1-antitrypsin polymers associated with different SERPINA1 genotypes | 1-gen-2024 | Balderacchi, Alice M.; Bignotti, Mattia; Ottaviani, Stefania; Denardo, Andrea; Barzon, Valentina; Ben Khlifa, Emna; Vailati, Guido; Piloni, Davide; Benini, Federica; Corda, Luciano; Corsico, Angelo G.; Ferrarotti, Ilaria; Fra, Annamaria |